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Table 5 Univariate and multivariate linear regression analyses of G6PD status (normal/intermediate/deficient), G6PD ViangchanG871A/G6PD wild type, and reticulocyte levels adjusted by gender, hemoglobin levels, postpartum age (day), ABO incompatibility, thalassemia, and hemoglobinopathies

From: Effect of neonatal reticulocytosis on glucose 6-phosphate dehydrogenase (G6PD) activity and G6PD deficiency detection: a cross-sectional study

Analysis type

Variable

Reticulocyte counts

B*

SE

Beta

p-value

Univariate

G6PD status (Spectrophotometric Assay) (Normal/Intermediate/Deficiency)

0.443

0.076

0.180

 < 0.001

G6PD status (Automated UV Enzymatic Assay) (Normal/Intermediate/Deficiency)

0.319

0.073

0.136

 < 0.001

G6PD Genotype

(Wildtype/Mutations)

0.807

0.126

0.197

 < 0.001

G6PD Genotype

(Wildtype/ G6PD ViangchanG871A / Others)

0.637

0.092

0.213

 < 0.001

Gender (Male/Female)

0.398

0.084

0.147

 < 0.001

Hemoglobin (≥ 15/ < 15 g/dL)

1.286

0.132

0.292

 < 0.001

Thalassemia and hemoglobinopathies

-0.158

0.209

-0.024

0.450

ABO incompatibility

1.956

0.498

0.162

 < 0.001

Postpartum age (day)

-0.314

0.053

-0.184

 < 0.001

Multivariate

G6PD status

(Automated UV Enzymatic Assay) (Deficiency/Intermediate/Normal)

0.316

0.093

0.129

0.001

Gender (Male/Female)

0.470

0.114

0.157

 < 0.001

Hemoglobin (≥ 15/ < 15 g/dL)

1.303

0.171

0.292

 < 0.001

ABO incompatibility (No/Yes)

1.225

0.466

0.102

0.009

Postpartum age (day)

-0.339

0.064

-0.203

 < 0.001

Constant

4.619

0.286

 

 < 0.001

Multivariate

G6PD Genotype

(Wildtype/Mutations)

0.630

0.165

0.144

 < 0.001

Gender (Male/Female)

0.438

0.114

0.146

 < 0.001

Hemoglobin (≥ 15/ < 15 g/dL)

1.264

0.171

0.283

 < 0.001

ABO incompatibility (No/Yes)

1.270

0.465

0.105

0.007

Postpartum age (day)

-0.332

0.064

-0.199

 < 0.001

Constant

4.984

0.254

 

 < 0.001