Table 1 Formulation of ANRC-EP (present study) and similar formulations used in Adams 2018 and Adams 2011 studies. The dosages are listed for 6 capsules, which is the daily dose for a 60 pound child; dosages are adjusted by bodyweight (1 capsule per 10 pounds bodyweight, to a maximum of 12 capsules for 120 pound or higher). Lower, gradually-increasing doses were recommended for the first month
From: Vitamin/mineral/micronutrient supplement for autism spectrum disorders: a research survey
| Â | ANRC Essentials Plus (current study) | 2018 study | 2011 study |
|---|---|---|---|
Vitamins | |||
 Vitamin A (Retinyl palmitate) | 2000 IU (600 mcg RAE) | 975 IU | 1000 IU |
 Carotenoids | 6000 IU vitamin A as mixed carotenoids | 5525 IU as beta carotene | 3.6 mg mixed carotenoids |
 Vitamin C (Calcium ascorbate) | 300 mg | 500 mg | 600 mg |
 Vitamin D (D3) | 2500 IU (62 mcg) | 1000 IU | 300 IU |
 Vitamin E (alpha tocopherol) | 67 IU ( 45 mg RAE) | 150 IU | 150 IU |
Mixed Tocopherols | 55Â mg of mixed tocopherols | Â | Â |
 Vitamin K | 300 mcg | 55 mcg (K1 and K2) | none |
200 mcg K1, 100 mcg K2 (as MK7) | Â | Â | |
 Vitamin B1 Thiamin (as thiamin hydrochloride) | 30 mg | 20 mg | 20 mg |
 Vitamin B2 Riboflavin | 40 mg | 40 mg | 20 mg |
 Vitamin B3 Niacin | 20 mg Niacin (nicotinic acid) | 25 mg (as inositol hexanicotinate) | 15 mg niacin |
20Â mg Niacinamide | 10Â mg Niacinamide | 10Â mg Niacinamide | |
10Â mg Nicotinamide Adenine Dinucleotide (NADH) | None | none | |
10Â mg nicotinamide riboside | none | none | |
 Vitamin B5 Pantothenic Acid (as calcium d-pantothenate) | 30 mg | 30 mg | 15 mg |
 Vitamin B6 | 40 mg | 40 mg | 40 mg |
20Â mg pyridoxine hydrochloride, 20Â mg pyridoxal 5 phosphate (P5P) | 20Â mg pyridoxine hydrochloride, 20Â mg pyridoxal 5 phosphate (P5P) | pyridoxine HCL | |
 Vitamin B12 | 600 mcg | 500 mcg | 500 mcg |
500 mcg as hydroxocobalamin and 100 mcg methylcobalamin | 250 mcg as methylcobalamin and 250 mcg as cyanocobalamin | cyanocobalamin | |
 Folate | 600 mcg | 600 mcg | 550 mcg |
MTHF (methyl-tetra-hydrofolate) | (as folic acid, folinic acid, & L-5-methyltetrahydrofolate) | folinic acid | |
 Biotin | 500 mcg | 225 mcg | 150 mcg |
Minerals | |||
 Calcium | 200 mg | 70 mg | 100 mg |
(as calcium ascorbate, calcium pantothenate, di-calcium malate) | (as calcium ascorbate) | (as calcium ascorbate) | |
 Chromium | 70 mcg | 70 mcg | 70 mcg |
(as chromium picolinate) | (as chromium amino acid chelate) | (as chromium amino acid chelate) | |
 Iodine | 100 mcg | 100 mcg | 100 mcg |
(as potassium iodide) | Â | Â | |
 Magnesium | 200 mg | 100 mg | 100 mg |
(as Mg Citrate (75Â mg elemental Mg), Mg Taurate (50Â mg elemental Mg), Di-Magnesium Malate (75Â mg elemental Mg) | as magnesium citrate | (as magnesium chloride hexahydrate) | |
 Manganese | 0.5 mg | 1 mg | 3 mg |
(as manganese aspartate) | (as manganese amino acid chelate) | (as manganese amino acid chelate) | |
 Molybdenum | 100 mcg | 100 mcg | 150 mcg |
(as molybdenum glycinate) | (sodium molybdate dihydrate) | (sodium molybdate dihydrate) | |
 Potassium (as potassium chloride) | 50 mg | 50 mg | 50 mg |
 Selenium (80% as selenomethionine, 20% as sodium selenite) | 50 mcg | 40 mcg | 22 mcg |
 Zinc | 15 mg | 15 mg | 12 mg |
(50% as zinc sulfate, 50% as amino acid chelate) | (as zinc gluconate) | (as zinc gluconate) | |
Other Nutrients | |||
 Choline | 250 mg | 250 mg | 250 mg |
(as choline bitartrate) | (as choline bitartrate) | choline chloride | |
 Co-Enzyme Q10 (ubiquinone) | 100 mg | 50 mg | 50 mg |
 Inositol | 100 mg | 100 mg | 100 mg |
 Carnitine | 300 mg | 200 | none |
l-carnitine | acetyl-l-carnitine | Â | |
 Lithium (as lithium orotate) | 350 mcg | 350 mcg | 500 mcg |
 Methylsulfonylmethane (MSM) | 500 mg | 500 mg | 500 mg |
 N-acetyl-cysteine | 100 mg | 45 mg | 50 mg |
 Taurine (as Mg taurate) | 514 mg | None | none |
 Vanadium | none | 25 mcg | none |
 Boron | none | 250 mcg | none |