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Table 2 Biochemical parameters in control, children with pneumonia, and children with pneumonia and asthma

From: The effects of asthma on the oxidative stress, inflammation, and endothelial dysfunction in children with pneumonia

Variable

mean ± SD

children with pneumonia and asthma (group I)

n = 25

children with pneumonia (group II)

n = 25

Healthy children (group III)

n = 25

P value

For ANOVA

TAC (mmol/l)

0.99 ± 0.22

1.23 ± 0.21

1.46 ± 0.19

<  0.001

MDA (μmol/l)

2.57 ± 0.40

2.11 ± 0.26

1.89 ± 0.27

<  0.001

TNF-α (pg/ml)

6.94 ± 1.61

5.54 ± 1.84

3.42 ± 1.32

<  0.001

VCAM-1 (mmol/l)

1.5 ± 0.62

1.06 ± 0.53

0.6. ±0.35

<  0.001

PAI-I (AU/ml)

10.52 ± 3.2

8.23 ± 3.4

2.39 ± 0.83

<  0.001

  1. Data are presented as mean value and standard deviation (SD); Indicator the presence or absence of a significant difference between the values of similar variables in the three groups (P value), MDA Malondialdehyde, TAC Total antioxidant capacity, VCAM-1 Vascular cell adhesion molecule 1, PAI-1 Plasminogen activator inhibitor-1, TNF-α Tumor necrosis factor alpha
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BMC Pediatrics

ISSN: 1471-2431

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