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Table 3 Anthropometric characteristics and laboratory markers at baseline and at the end of study

From: The effects of chitosan supplementation on anthropometric indicators of obesity, lipid and glycemic profiles, and appetite-regulated hormones in adolescents with overweight or obesity: a randomized, double-blind clinical trial

 

Chitosan

Placebo

P-valueb

 

Baseline

After

Change

P-valuea

Baseline

After

Change

P-valuea

Weight (kg)

56.12 (7.20)

52.54 (7.07)

−3.58 (2.17)

< 0.001

57.67 (9.34)

57.40 (9.45)

−0.27 (1.85)

0.252

< 0.001

BMI (kg/m2)

25.31 (1.79)

23.70 (1.93)

−1.61 (0.99)

< 0.001

24.71 (1.86)

24.60 (2.05)

−0.10 (0.86)

0.102

< 0.001

BMI (Z-score)

1.52 (0.26)

1.24 (0.36)

−0.28 (0.19)

< 0.001

1.67 (0.32)

1.65 (0.35)

−0.02 (0.12)

0.247

< 0.001

WC (cm)

88.48 (15.15)

83.48 (15.18)

−5.00 (3.11)

< 0.001

93.40 (16.39)

92.40 (16.56)

−1.00 (2.37)

0.011

< 0.001

FBG (mg/dL)

96.19 (10.15)

90.41 (8.81)

−5.77 (6.93)

< 0.001

95.26 (9.89)

94.40 (9.82)

−0.86 (3.92)

0.237

0.131

HOMA-IR

2.37 (0.89)

2.13 (0.70)

−0.24 (0.44)

< 0.001

2.89 (1.37)

2.51 (0.93)

−0.38 (0.70)

0.001

0.370

Insulin (μIU/mL)

23.23 (11.85)

17.71 (8.44)

−5.51 (7.52)

0.001

22.11 (14.64)

23.95 (12.49)

1.84 (11.57)

0.206

0.006

TC (mg/dL)

182.09 (27.40)

167.96 (26.22)

−14.12 (13.34)

< 0.001

167.90 (21.92)

163.93 (21.62)

−3.96 (5.39)

< 0.001

0.071

TG (mg/dL)

149.64 (45.70)

143.96 (40.43)

−5.67 (9.24)

< 0.001

125.56 (29.84)

121.70 (28.54)

−3.86 (5.31)

0.001

0.847

HDL-C (mg/dL)

43.54 (9.58)

45.38 (8.53)

1.83 (4.64)

0.041

43.96 (8.34)

44.46 (8.16)

0.50 (1.73)

0.162

0.116

LDL-C (mg/dL)

114.43 (33.82)

107.25 (37.06)

−7.18 (10.16)

< 0.001

120.60 (26.21)

115.86 (25.29)

−4.73 (10.16)

0.016

0.714

Adiponectin (ng/mL)

7.55 (4.20)

9.24 (5.42)

1.69 (2.13)

< 0.001

10.09 (5.32)

8.93 (3.81)

−1.15 (3.06)

0.075

0.028

Leptin (ng/mL)

47.66 (35.13)

28.25 (20.73)

−19.40 (16.89)

< 0.001

50.04 (44.59)

40.90 (33.80)

−9.26 (26.78)

0.382

0.046

NPY (ng/mL)

207.56 (123.54)

165.59 (99.45)

−41.96 (79.34)

0.009

228.24 (155.04)

233.62 (155.82)

5.38 (45.99)

0.910

0.278

  1. Data are expressed as Mean (SD)
  2. Abbreviations: BMI Body mass index, FBG Fasting blood glucose, HDL-C High density lipoprotein-cholesterol, HOMA_IR Homeostatic model assessment-insulin resistance, LDL-C Low density lipoprotein-cholesterol, NPY Neuropeptide Y, TC Total cholesterol, TG Triglycerides, WC Waist circumference
  3. a P-values for comparison of within-group differences by Wilcoxon signed-rank test
  4. b P value for between-group comparison using analyses of covariance (ANCOVA), considering baseline values (weight, BMI, WC, TG, TC, physical activity, adiponectin, and energy) as covariate
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BMC Pediatrics

ISSN: 1471-2431

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