Interaction between serum cotinine and body mass index on asthma in the children: a cross-sectional study

BMC Pediatrics

Table 3 The interaction between serum cotinine levels and BMI on asthma in different gender

	Male		Female
	OR (95%CI)	P	OR (95%CI)	P
Interaction¹ Low-level serum cotinine and Group A	Ref		Ref
Low-level serum cotinine and Group B	1.338 (1.01–1.771)	0.042	1.295 (0.942–1.780)	0.111
Low-level serum cotinine and Group C	1.541 (1.192–1.994)	0.001	1.893 (1.400–2.559)	< 0.001
High-level serum cotinine and Group A	1.184 (0.852–1.646)	0.311	1.236 (0.902–1.693)	0.186
High-level serum cotinine and Group B	1.360 (0.845–2.189)	0.203	1.390 (0.889–2.171)	0.147
High-level serum cotinine and Group C	1.832 (1.206–2.783)	0.005	1.814 (1.256–2.618)	0.002
Interaction
Attributable proportion of interaction (95%CI)	0.173 (0.005–0.351)		0.254 (0.061–0.447)
Synergy index (95%CI)	1.934 (1.344–2.783)		2.225 (1.813–2.732)

Ref, reference; OR: odds ratio; CI Confidence interval, BMI Body mass index, Group A: underweight and normal weight (< 85th percentile); Group B: overweight (≥ 85th percentile to < 95th percentile); and Group C: obesity (≥ 95th percentile)
¹ low-level serum cotinine: < 0.0436 ng/ml and high-level serum cotinine: ≥ 0.0436 ng/ml
The multivariate model adjusted for age, gender, ethnicity, gender of the household reference person, and marital status of the household reference person

ISSN: 1471-2431