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Table 6 Model 7-Results of a multivariable linear regression model testing the association between birthweight (adjusted for sex and gestational age), maternal clinical characteristics (n = 549 parent-offspring trios), parental heights, and maternal and fetal genetic scores. R2 = 0.294; Adj-R2 = 0.280

From: Assessing whether genetic scores explain extra variation in birthweight, when added to clinical and anthropometric measures

Variable

Change in birthweight (g) per 1 SD change in independent variable

95% Confidence Interval

t-value

p-value

Intercept

3799

3669, 3929

57.1

<2e-16

Maternal age

−53

−87, −19

−3.1

0.002

Maternal weight

98

62, 135

5.3

2e-07

Mother’s smoking status

−241

−335, − 147

−5.0

7e-07

Parity

−217

− 283, −150

−6.4

4e-10

Mother’s fasting glucose at 28 weeks’ gestation

101

66, 136

5.7

3e-08

Maternal height

39

4, 74

2.2

0.03

Paternal height

64

31, 96

3.7

0.0002

Maternal genetic score for offspring birthweight (adjusted for fetal effects)

60

27, 92

3.6

0.0003

Fetal genetic score for offspring birthweight (adjusted for maternal effects)

57

25, 89

3.5

0.0004