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Table 5 Model 6-Results of a multivariable linear regression model testing the association between birthweight (adjusted for sex and gestational age), maternal clinical characteristics (n = 549 parent-offspring trios), and parental heights and genetic scores. R2 = 0.285; Adj-R2 = 0.271

From: Assessing whether genetic scores explain extra variation in birthweight, when added to clinical and anthropometric measures

Variable

Change in birthweight (g) per 1 SD change in independent variable

95% Confidence Interval

t-value

p-value

Intercept

3796

3665, 3927

56.7

<2e-16

Maternal age

−54

−88, −20

−3.1

0.002

Maternal weight

97

60, 134

5.1

4e-07

Mother’s smoking status

−241

− 335, −146

−5.0

8e-07

Parity

− 211

--278, − 144

−6.2

1e-09

Mother’s fasting glucose at 28 weeks’ gestation

104

69, 140

5.8

2e-08

Maternal height

44

9, 80

2.5

0.01

Paternal height

61

28, 95

3.6

0.0003

Maternal genetic score for offspring birthweight (adjusted for fetal effects)

57

25, 90

3.5

0.0006

Paternal genetic score for father’s own birthweight

39

6, 71

2.3

0.02