Table 3 Postoperative data of the two groups
From: Predictive factors contributing to prolonged recovery in patients after Fontan operation
Prolonged recovery (N = 70) | Standard recovery (N = 212) | P-value | |
|---|---|---|---|
Mechanical ventilation time (h), median (IQR) | 44 (20–95) | 10 (8–20) | < 0.001* |
Mechanical ventilation time, n (%) | < 0.001* | ||
≤ 12 h | 12 (17.1%) | 133 (62.7%) | |
12–24 h | 14 (20.0%) | 57 (26.9%) | |
24–48 h | 15 (21.4%) | 16 (7.5%) | |
> 48 h | 29 (41.4%) | 6 (2.8%) | |
P/F ratio after extubation, median (IQR) | 168.15 (138.64–196.79) | 202.06 (165.97–249.03) | < 0.001* |
Hemodynamics in POD 0 | |||
mPAP (mmHg), mean ± SD | 18.13 ± 3.101 | 16.80 ± 2.807 | 0.002* |
mABP (mmHg), mean ± SD | 58.27 ± 9.095 | 63.45 ± 9.101 | < 0.001* |
Pp/Ps, mean ± SD | 0.32 ± 0.077 | 0.27 ± 0.067 | < 0.001* |
PH treatment after Fontan operation, n (%) | 63 (90.0%) | 139 (65.6%) | < 0.001* |
Drugs in treating PH, n (%) | 0.034* | ||
Endothelin receptor antagonists | 13 (20.6%) | 51 (37.0%) | |
Prostacyclin analogues | 16 (25.4%) | 20 (14.5%) | |
Combined | 34 (54.0%) | 67 (48.6%) | |
PH treatment within two days, n (%) | 57 (81.4%) | 127 (59.9%) | 0.001* |
Chest drainage time (day), median (IQR) | 13 (10–18) | 9 (7–14) | < 0.001* |
Total drainage volume (ml/kg), median (IQR) | 93.12 (62.50–129.56) | 41.55 (28.48–61.82) | < 0.001* |
Drainage volume within two days (ml/kg), median (IQR) | 67.50 (51.25–87.11) | 39.38 (27.01–57.89) | < 0.001* |
Volume resuscitation within two days (ml/kg), n (%) | 132.14 (96.88–185.71) | 78.46 (51.72–111.00) | < 0.001* |
Inotropic score (IS), median (IQR) | |||
IS in POD 0 (μg/kg/min) | 20.5 (13.5–35) | 15 (10.5–18.5) | < 0.001* |
IS in POD 1 (μg/kg/min) | 20 (13–30) | 11 (7.5–14.3) | < 0.001* |
IS in POD 2 (μg/kg/min) | 17 (10–29.6) | 8 (6–12.5) | < 0.001* |
Surgical reintervention, n (%) | 16 (22.9%) | 11 (5.2%) | < 0.001* |
Hospital stay (day), median (IQR) | 21 (15–28) | 15 (12–19) | < 0.001* |
Hospitalization costs (dollar), mean ± SD | 18,093.81 ± 6953.094 | 12,535.55 ± 10,039.343 | < 0.001* |
Readmission within two months after discharge, n (%) | 13 (18.6%) | 18 (8.5%) | 0.019* |
Complications | |||
Hypoxemia, n (%) | 49 (70%) | 66 (31.1%) | < 0.001* |
cardiac output syndrome, n (%) | 44 (62.9%) | 53 (25.0%) | < 0.001* |
Liver disfunction, n (%) | 26 (37.1%) | 34 (16.0%) | < 0.001* |
Arrhythmia n (%) | 24 (34.3%) | 60 (28.3%) | 0.343 |
disfunction, n (%) | 20 (28.6%) | 17 (8.0%) | < 0.001* |
Atrioventricular valve regurgitation, n (%) | 13 (18.6%) | 21 (9.9%) | 0.054 |