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Table 5 Multiple linear regression analysis of factors correlating with total and verbal IQ

From: RANK/RANKL/OPG axis genes relation to cognitive impairment in children with transfusion-dependent thalassemia: a cross-sectional study

 

Total IQ

Verbal IQ

Standardized coefficient (𝛃)

t

p

Standardized coefficient (𝛃)

t

p

RANK rs1805034 (C > T)

− 0.17

−1.67

0.009*

− 0.21

− 2.2

0.03*

RANKL rs2277438 (G > A)

–

 

–

0.1

0.39

0.06

Age (years)

−0.51

−4.83

0.001*

−0.58

−5.7

0.001*

Serum ferritin (ng/ml)

−0.23

−2.23

0.03*

−0.22

− 2.2

0.02*

R2

R2 = 0.4

(F = 11.8; df = 3)

R2 = 0.5

(F = 13.9; df = 4)

  1. * Statistical significance p < 0.05
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BMC Pediatrics

ISSN: 1471-2431

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