Skip to main content

Table 4 Correlations of factors affecting total, verbal, and performance IQ in TDT children

From: RANK/RANKL/OPG axis genes relation to cognitive impairment in children with transfusion-dependent thalassemia: a cross-sectional study

 

Total IQ

Verbal IQ

Performance IQ

r

p

r

p

r

p

RANK rs1805034 (C > T)

−0.33

0.01*

−0.33

0.009*

–

–

RANKL rs2277438 (G > A)

–

–

0.38

0.01*

–

–

G allele of RANKL rs2277438 (G > A)

0.22

0.79

–

–

0.25

0.05

Age (years)

−0.54

0.001*

− 0.63

0.001*

− 0.32

0.01*

Sex

0.08

0.5

0.21

0.09

0.1

0.4

Socioeconomic level

0.18

0.15

0.2

0.06

0.17

0.17

BMI

0.113

0.3

0.12

0.3

−0.09

0.4

Pre-transfusion Hb (gm%)

0.09

0.4

0.09

0.4

0.04

0.7

Serum ferritin (ng/ml)

−0.32

0.01*

−0.33

0.009*

−0.28

0.02*

LIC (mg/g dry weight)

−0.019

0.8

0.13

0.3

0.02

0.8

  1. Hb hemoglobin, BMI body mass index, LIC liver iron concentration.
  2. * Statistical significance p < 0.05