Fig. 3
From: MYCN protein stability is a better prognostic indicator in neuroblastoma
Conjoint analysis of IHC and FISH provides better prognostic prediction. a-b Survival curve analysis of EFS cut off by IHC score in the MYCN FISH+ group (n = 16) (a) and MYCN FISH− group (n = 25) (b). Log-rank (Mantel-Cox) test was used to generate the p-value. To ensure prognostic accuracy for individuals, only 41 patients (including 16 with MYCN FISH+ tumors and 25 with MYCN FISH− tumors) diagnosed in or before 2016 were included from the cohort of 53 patients. c Survival curve analysis of EFS cut off by IHC and FISH results (n = 41). Log-rank (Mantel-Cox) test was used to generate the p-value. Sample selection was the same with 3a-b. d The chromaticity diagram of several significant clinical factors