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Fig. 9 | BMC Pediatrics

Fig. 9

From: Prognostic analysis of E2F transcription factors E2F1 and E2F3 in four independent pediatric neuroblastoma cohorts

Fig. 9

Genes associated with the E2F1 and E2F3 expressions are enriched in cell cycle signaling pathway. a Transcription factors associated with E2F1 and E2F3 expressions. b Signaling pathways associated with the E2F1 and E2F3 expressions. Genes enriched in cell cycle signaling pathway were showed. c Forest plots showed the associations of cell cycle signaling pathway with the neuroblastoma event free survival in TARGET, GSE16476, GSE85047 and E-MTAB-1781 datasets. d Forest plots showed the associations of cell cycle signaling pathway with the neuroblastoma overall survival. e The Kaplan–Meier curves showed the different event free survival of pediatric neuroblastoma patients with higher or lower cell cycle signaling pathway in TARGET, GSE16476, GSE85047 and E-MTAB-1781 datasets. f Different overall survival of pediatric neuroblastoma patients with higher or lower cell cycle signaling pathway in TARGET, GSE16476, GSE85047 and E-MTAB-1781 datasets

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BMC Pediatrics

ISSN: 1471-2431

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