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Table 3 Complications and main treatmentsa

From: Risk factors of extrauterine growth restriction in very preterm infants with bronchopulmonary dysplasia: a multi-center study in China

 

EUGR

Non–EUGR

Z

P

Subjects, n

450

560

—

—

NRDS

374 (83.1)

440 (78.6)

3.288

0.070

Postnatal glucocorticoid therapy

153 (34.0)

141 (25.2)

9.409

0.002

hsPDA

144 (32.0)

124 (22.1)

12.436

 < 0.001

Interventional ROP

39 (8.7)

20 (3.6)

11.777

0.001

Anemia requires blood transfusion

386 (85.8)

418 (74.6)

19.053

 < 0.001

Feeding intolerance

218 (48.4)

195 (34.8)

19.158

 < 0.001

NEC Bell stage ≥ 2

40 (8.9)

52 (9.3)

0.047

0.828

MBDP

23 (5.1)

15 (2.7)

4.077

0.043

IVH grade III–IV

12 (2.7)

16 (2.9)

0.034

0.855

Periventricular leukomalacia

24 (5.3)

18 (3.2)

2.811

0.094

Early–onset sepsis

84 (18.7)

106 (18.9)

0.011

0.916

Late–onset sepsis

105 (23.3)

74 (13.2)

17.521

 < 0.001

PNAC

88 (19.6)

61 (10.9)

14.888

 < 0.001

Invasive mechanical ventilation, db

3 (0, 10)

1 (0, 5)

–6.400

 < 0.001

Total hospital stay, d b

62 (50, 75)

53 (45, 66)

–6.553

 < 0.001

  1. aReported as n (%), unless indicated otherwise; b[M (Q1, Q3)]
  2. hsPDA Hemodynamically significant patent ductus arteriosus, IVH Intraventricular hemorrhage, NEC Neonatal necrotizing enterocolitis, NRDS Neonatal respiratory distress syndrome, MBDP Metabolic bone disease of prematurity, PNAC Parenteral nutrition-associated cholestasis, ROP Retinopathy of prematurity