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Fig. 3 | BMC Pediatrics

Fig. 3

From: Failure of crizotinib based systemic treatment in ALK positive histiocytosis involving the central nervous system: a case report and literature review

Fig. 3

The management of CSF and the lung CT during chemotherapy. The SDE did not relieve on day 1 (A) and day 7 (B) after burr hole drainage. SE gradually relieved on day 1 (C) and day 7 (D) after implanting the Ommaya reservoir. SE gradually relieved on day 1 (E) and day 7 (F) after implanting a long-distance open ventricular drainage operation. The nodes (red arrow) on the lungs did not shrink one month (G and H) and two months (I and J) after the management of treatment with crizotinib and vincristine. After two months of cytarabine, crizotinib, and vincristine treatment, lesion remission was observed (K and L). The measured resolution for images was 360 ppi

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