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Table 3 Comparison between Obese and non-obese (pre and post KT) regarding different study parameters

From: Effect of pre and post-transplant body mass index on pediatric kidney transplant outcomes

 

BMI post-KT

P-value

BMI pre-KT

P-value

Non obese (n = 12)

Obese (n = 38)

Non obese (n = 36)

Obese (n = 14)

No. (%) / Mean ± SD

No. (%) / Mean ± SD

No. (%) / Mean ± SD

No. (%) / Mean ± SD

Sex

 Male

5 (41.7)

25 (65.8)

0.137

22 (61.1)

8 (57.1)

0.797

 Female

7 (58.3)

13 (34.2)

14 (38.9)

6 (42.9)

Age (years)

 5–10

6 (50)

2 (5.3)

0.001٭

7 (19.4)

1 (7.1)

0.102

 10–15

6 (50)

27 (71.1)

25 (69.5)

8 (57.1)

  > 15

0 (0)

9 (23.7)

4 (11.1)

5 (35.8)

Residence

 Urban

5 (41.7)

26 (68.4)

0.096

22 (61.1)

9 (64.3)

0.836

 Rural

7 (58.3)

12 (31.6)

14 (38.9)

5 (35.7)

Acute rejection › 6 ms

 No

2 (16.7)

3 (7.9)

0.377

4 (11.1)

1 (7.1)

0.675

 Yes

10 (83.3)

35 (92.1)

32 (88.9)

13 (92.9)

Acute rejection < 6 ms

 No

12 (100)

26 (68.4)

0.026٭

32 (88.9)

6 (42.9)

0.001٭

 Yes

0 (0)

12 (31.6)

4 (11.1)

8 (57.1)

Chronic rejection

 No

12 (100)

23 (60.5)

0.009٭

28 (77.8)

7 (50)

0.05*

 Yes

0 (0)

15 (39.5)

8 (22.2)

7 (50)

Graft survival

  < 5 yrs

10 (83.3)

29 (76.3)

0.047*

26 (72.2)

13 (92.9)

0.114

 > 5 yrs

2 (16.7)

9 (23.7)

10 (27.8)

1 (7.1)

HTN pre- transplantation

 No

12 (100)

25 (65.8)

0.019٭

29 (80.6)

8 (57.1)

0.090

 Yes

0 (0)

13 (34.2)

7 (19.4)

6 (42.9)

HTN post-transplantation

 No

8 (66.7)

18 (47.4)

0.243

21 (58.3)

5 (35.7)

0.151

 Yes

4 (33.3)

20 (52.6)

15 (41.7)

9 (64.3)

Impaired FBG

 No

12(100)

19 (50)

0.005٭

30 (83.3)

2 (14.3)

 < 0.001٭

 Yes

0 (0)

19 (50)

6 (16.7)

12 (85.7)

Impaired OGTT

 No

12(100)

20 (52.6)

0.007٭

29 (80.5)

2 (14.3)

 < 0.001٭

 Yes

0 (0)

18 (47.4)

7 (19.5)

12 (85.7)

Urinary ACR

 Normal

10 (83.3)

3 (7.9)

 < 0.001٭

24 (67.7)

5 (35.7)

0.002*

 High

2 (16.7)

35 (92.1)

12 (33.3)

9 (64.3)

Cholesterol (mg/dl)

193.75 ± 31.94

228.16 ± 50.7

0.032٭

208.31 ± 45.61

249.71 ± 45.59

0.006٭

TG (mg/dl)

124.08 ± 20.13

155.66 ± 81.58

0.193

132.42 ± 34.68

188.36 ± 119.67

0.013٭

LDL (mg/dl)

127.42 ± 31.15

160.24 ± 26.41

0.001٭

144.42 ± 30.66

172.79 ± 20.17

0.002٭

HDL (mg/dl)

65.08 ± 15.23

48.89 ± 10.64

0.000٭

55 ± 14.17

47.07 ± 10.64

0.065

HbA1c (%)

5.13 ± 0.2

5.58 ± 0.46

0.003٭

5.31 ± 0.3

5.89 ± 0.44

0.001

  1. BMI Body Mass Index, SD Standard Deviation, KT Kidney Transplantation, FBG Fasting Blood Glucose, TG Triglycerides, OGTT Oral Glucose Tolerance test, ACR Albumin Creatinine Ratio, HDL High Density Lipoprotein, LDL Low Density Lipoprotein, HbA1c Glycosylated Hemoglobin
  2. *p-value less than 0.05 and it is statistically significant