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Table 3 Bivariate and Multivariate Cox regression analysis results of Asphyxiated babies who were admitted at NICUs of Addis Ababa public hospitals, Ethiopia, 2021 [n = 411]

From: Survival and predictors of asphyxia among neonates admitted in neonatal intensive care units of public hospitals of Addis Ababa, Ethiopia, 2021: a retrospective follow-up study

Covariates

CHR (95% CI)

P-value

AHR (95% CI)

P- value

Maternal Age

  20 – 34 years

1

 

1

 

  < 20 years

0.94(0.58 – 1.52)

0.812

1.22(0.73—2.04)

0.455

  > 34 years

1.34(0.92 – 1.94)

0.120

1.28(0.85—1.95)

0.241

Place of residency

  Addis Ababa

1

 

1

 

  Out of Addis Ababa

0.78(0.58 – 1.05)

0.105

0.89(0.64- 1.23)

0.479

Mode of delivery

  SVD

1

 

1

 

  Assisted delivery

0.92(0.66 – 1.27)

0.621

0.89(0.62—1.26)

0.506

  C/S delivery

0.81(0.62 – 1.04)

0.107

0.89(0.66—1.19)

0.418

Prolonged labor

  No

1

 

1

 

  Yes

1.26(0.92 – 0.74)

0.142

1.21(0.85 -1.71)

0.292

Birth weight

  Normal

1

 

1

 

  Big baby

1.16( 0.71 – 1.91)

0.554

1.24(0.70—2.19)

0.454

  Low birth weight

0.63(0.48—0.83)

0.001

0.67(0.47—0.96)

0.029 *

Gestational Age

  Term

1

 

1

 

  Post term

0.60( 0.42 – 0.85)

0.004

0.96(0.61—1.50)

0.841

  Preterm

0.87(0.59 -1.29)

0.494

0.93(0.59—1.46)

0.753

Age at presentation

   < 24 h

1

 

1

 

  24 – 72 h

0.82(0.49 – 1.38)

0.470

0.45(0.16—1.23)

0.121

   > 72 h

0.45(0.22—0.92)

0.031

0.64( 0.28—1.43)

0.275

Fifth minutes APGAR

   ≥ 7

1

 

1

 

   < 7

0.81(0.64—1.03)

0.091

1.03(0.78—1.35)

0.838

Meconium aspiration syndrome

  No

1

 

1

 

  Yes

0.83(0.65—1.05)

0.121

0.89(0.68—1.16)

0.386

Hyperbilirubinemia

  No

1

 

1

 

  Yes

0.76(0.51—1.14)

0.191

1.28(0.81—2.01)

0.285

Necrotizing Enterocolitis

  No

1

 

1

 

  Yes

0.46(0.24—0.91)

0.025

0.64(0.30—1.36)

0.245

Acute kidney injury

  No

1

 

1

 

  Yes

0.69(0.40—1.18)

0.171

0.90 (0.49—1.64)

0.726

Thrombocytopenia

  No

1

 

1

 

  Yes

0.45(0.26 -0.75)

0.003

0.44(0.24—0.80)

0.007 **

Aminophylline

  No

1

 

1

 

  Yes

0.48(0.26 -0.89)

0.019

0.80(0.40—1.58)

0.515

Oxygenation

  No

1

 

1

 

  Yes

0.57(0.40—0.82)

0.002

0.69(0.45—1.07)

0.095

Resuscitation at delivery

  No

1

 

1

 

  Yes

0.80(0.60—1.07

0.134

1.00(0.71—1.41)

0.994

Ca±± gluconate

  No

1

 

1

 

  Yes

0.61(0.48—0.79)

0.000

0.75(0.58—0.99)

0.039 *

  1. NB:- *Significant (P-value < 0.05), **significant (p-value < 0.01) and HR = 1 is reference variable