Table 5 Comparative yield of positive microbiological results obtained for viruses and atypical bacteria in 525 children and adolescents with community acquired pneumonia
Microorganism, n (%) | mPCR | IFA | Paired Serology | IFA + mPCR | Paired Serology + mPCR | IFA + Paired Serology | IFA + mPCR + Paired Serology | Total cases of CAP attributed to each microorganisma |
|---|---|---|---|---|---|---|---|---|
Respiratory Syncytial Virus A and B | 64 (39) | 11 (6.7) | 37 (22.6) | 13 (7.9) | 24 (14.6) | 5 (3) | 10 (6.1) | 164 |
Parainfluenza virus 1/2/3/4 | 48 (39.3) | 22 (18) | 30 (24.6) | 4 (3.3) | 11 (9) | 2 (1.6) | 5 (4.1) | 122 |
Rhinovirus A/B/C | 111 (100) | NA | NA | NA | NA | NA | NA | 111 |
Influenza A and B | 40 (41.7) | 8 (8.3) | 37 (38.6) | 0 (0) | 7 (7.3) | 4 (4.2) | 0 (0) | 96 |
Adenovirus | 2 (2.9) | 19 (27.9) | 45 (66.2) | 0 (0) | 2 (2.9) | 0 (0) | 0 (0) | 68 |
Metapneumovirus | 37 (100) | NA | NA | NA | NA | NA | NA | 37 |
Coronavirus 229E/NL63and OC43 | 15 (100) | NA | NA | NA | NA | NA | NA | 15 |
Enterovirusb | 6 (100) | NA | NA | NA | NA | NA | NA | 6 |
Bocavirus 1/2/3/4b | 2 (100) | NA | NA | NA | NA | NA | NA | 2 |
Mycoplasma pneumoniae | 40 (54.8) | NA | 19 (26) | NA | 14 (19.2) | NA | NA | 73 |
Bordetella pertussis | 7 (28) | 17 (68) | 1 (4) | 0 (0) | NA | NA | NA | 25 |
Chlamydophila pneumoniae | 1 (10) | NA | 9 (90) | NA | 0 (0) | NA | NA | 10 |
Legionella pneumophila | 0 | NA | 9 (100) | NA | 0 | NA | NA | 9 |
Coxiella burnetii | NA | NA | 5 (100) | NA | NA | NA | NA | 5 |