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Table 7 Association of MTHFR haplotypes with risk of CHD

From: “Association of MTHFR and MS/MTR gene polymorphisms with congenital heart defects in North Indian population (Jammu and Kashmir): a case–control study encompassing meta-analysis and trial sequential analysis”

Variant MTHFR C677T/ G1793A

CHD Cases (n = 50)

Controls (n = 100)

OR (95% CI)

p-value

C-A

0.230

0.050

5.67 [2.58–12.48]

2.71e‐006a

C-G

0.690

0.895

0.26 [0.14–0.48]

1.00e‐005a

T-G

0.080

0.055

1.49 [0.58–3.84]

0.40

T-A

0.000

0.000

-

-

  1. aSignificant values, Fisher’s p-value