Table 3 Univariate analysis exploring the different risk factors for each infection

Male, gender

1.266 (0.894–1.792)

1.086 (0.749–1.575)

1.870 (0.951–3.677)

 < 3 months of age

1.254 (0.845–1.861)

1.232 (0.809–1.877)

1.637(0.705–3.804)

Previous comorbidities

0.981 (0.679–1.416)

0.816 (0.548–1.216)

2.4 (1.222–4.715)

Comorbidity’s types

 Prematurity

0.949 (0.631–1.427)

0.934 (0.604–1.445)

1.673 (0.817–3.428)

 Respiratory

0.310 (0.071–1.348)

0.394 (0.090–1.719)

0.932 (0.121–7.167)

 Cardiologic

1.173 (0.627–2.195)

0.639 (0.294–1.389)

3.186 (1.323–7.676)

 Neurological

1.740 (0.623–4.859)

1.670 (0.571–4.885)

1.189 (0.153–9.257)

 BROSJOD > 12

2.470 (1.428–4.271)

2.500 (1.422–4.396)

2.013 (0.739–5.482)

Viral etiology

 RSV

0.806 (0.563–1.153)

0.953 (0.648–1.400)

0.441 (0.225–0.866)

 Rhino/Enterovirus

0.958 (0.639–1.437)

0.862 (0.555–1.337)

1.630 (0.796–3.338)

 Metapneumovirus

0.810 (0.321–2.040)

1.037 (0.411–2.618)

0.944 (0.927–0.962)

 Influenza

0.647 (0.262–1.600)

0.504 (0.174–1.461)

1.912 (0.554–6.603)

 Viral co-infection

0.689 (0.444–1.069)

0.792 (0.500–1.253)

0.837 (0.3599–1.951)

 Bacterial co-infection

2.454 (1.263–4.769)

2.519 (1.278–4.964)

0.985 (0.228–4.265)

Received treatment and support

 Nebulized treatment

0.781 (0.510–1.196)

0.868 (0.549–1.372)

0.504 (0.241–1.053)

 Endotracheal mucolytic

3.632 (2.261–5.834)

3.234 (1.993–5.246)

5.344 (2.612–10.931)

 Inotropic support

4.893 (3.160–7.575)

4.354 (2.796–6.778)

3.882 (1.916–7.865)

 CMV

4.015 (2.798–5.760)

3.094 (2.122–4.509)

8.344 (3.596–19.360)

 CMV > 7 days

2.867 (1.943–4.231)

1.828 (1.207–2.767)

11.361 (5.335–24.197)

 Central line

4.839 (3.352–6.985)

3.683 (2.516–5.391)

8.721 (3.902–19.492)

 Central line > 7 days

4.283 (2.912–6.300)

3.050 (2.046–4.548)

9.162 (4.392–19.114)

 Urinary catheter

4.001 (2.789–5.739)

3.064 (2.102–4.464)

8.524 (3.673–19.778)

 Urinary catheter > 5 days

3.840 (2.669–5.524)

2.715 (1.858–3.967)

10.984 (4.726–25.533)

 ECMO

2.890 (0.578–14.45)

1.823 (0.331–10.052)

19.273 (3.746–99.167)