Table 1 Demographic and clinical data, including the comparison between No-IBI group and BI group
Variables | Total (n = 675) | No-BI (n = 500) | BI (n = 175) | p value |
|---|---|---|---|---|
Gender (male), n (%) | 399 (59.1) | 303 (60.6) | 96 (54.9) | 0.184 |
Age (days) | 47 (25–99) | 48.5 (25–100.8) | 44 (24–88) | 0.556 |
< 3 months of age, n (%) | 487 (72.1) | 355 (71) | 132 (75.4) | 0.261 |
Previous comorbidities, n (%) | 222 (32.9) | 165 (33) | 57 (32.6) | 0.917 |
Prematurity | 159 (23.6) | 119 (23.8) | 40 (22.9) | 0.800 |
Respiratory | 20 (3) | 18 (3.6) | 2 (1.1) | 0.122 |
Cardiac | 52 (7.7) | 37 (7.4) | 15 (8.6) | 0.617 |
Neurological | 16 (2.4) | 10 (2) | 6 (3.4) | 0.285 |
Others | 36 (5.3) | 24 (4.8) | 12 (6.9) | 0.297 |
BROSJOD, median (IQR) | 9 (7–11) | 9 (7–11) | 10 (8–12) | 0.001 |
PRISM, median (IQR) | 0 (0–3) | 0 (0–3) | 3 (0–6) | < 0.001 |
Viral etiology, n (%) | ||||
RSV | 445 (65.9) | 336 (67.2) | 109 (62.3) | 0.238 |
Rhino/Enterovirus | 168 (24.9) | 121 (24.2) | 41 (23.4) | 0.837 |
Metapneumovirus | 27 (4) | 21 (4.2) | 6 (3.4) | 0.654 |
Influenza | 32 (4.7) | 26 (5.2) | 6 (3.4) | 0.343 |
Viral co-infection, n (%) | 150 (22.2) | 119 (23.8) | 31 (17.7) | 0.096 |
LOS, median days (IQR) | ||||
PICU | 6 (4–11) | 6 (4–9.8) | 9 (5–13) | < 0.001 |
Hospitalization | 8 (12–19) | 11 (8–19) | 14 (9–20) | 0.003 |
Antibiotherapy, n (%) | 542 (80.3) | 371 (74.2) | 171 (97.7) | < 0.001 |
Respiratory support | ||||
CMV, n (%) | 241 (35.7) | 136 (27.2) | 105 (60.0) | < 0.001 |
Days, median (IQR) | 7.9 (5.5–10.6) | 8 (5.6–10.3) | 7.9 (5.4–10.9) | 1.000 |
NIV, n (%) | 627 (92.9) | 463 (92.6) | 164 (93.7) | 0.622 |
Days, median (IQR) | 3.3 (2–5.1) | 3.3 (2.1–4.9) | 3.3 (1.9–4.9) | 0.521 |
Inotropic support, n (%) | 104 (15.4) | 46 (9.2) | 58 (33.1) | < 0.001 |
ECMO, n (%) | 6 (0.9) | 3 (0.6) | 3 (1.7) | 0.183 |
Mortality, n (%) | 9 (1.3) | 5 (1) | 4 (2.3) | 0.248 |