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Table 1 Characteristics of included studies

From: Child transmission of SARS-CoV-2: a systematic review and meta-analysis

Article

Number of index patients

Child-to-child transmission

Child-to-adult transmission

Country

Setting

Positive PCR

Symptomatic; unconfirmed PCR

Asymptomatic or negative PCR

Positive PCR

Symptomatic; unconfirmed PCR

Asymptomatic or negative PCR

Posfay-Barbe et al. 2020

39

0

6

13

2

11

11

Switzerland

Household

Laws et al. 2021

12

1

0

15

2

0

17

USA

Household

Lopez et al. 2020

4

1

2

--

7

2

--

USA

Household

Macartney et al. 2020

12

2

--

196

1

--

101

Australia

Childcare

Yoon et al. 2021

1

0

1

153

0

1

35

South Korea

Childcare

Ehrhardt et al. 2020a

6

11

--

--

--

--

--

Germany

Childcare

Heavey et al. 2020

3

0

0

895

0

0

94

Ireland

School

Kim et al. 2021b

1

1

--

--

--

--

2

South Korea

Household

Drezner et al. 2020c

1

0

0

10

--

--

--

USA

Soccer

Gharekhanloo, Sedighi, and Khazaei 2020

1

1

0

0

0

0

0

Iran

Household

Wong et al. 2020d

1

0

0

 

1

0

 

South East Asia

School

Schwartz et al. 2020e

1

0

3

4

6

2

4

USA

Family gathering

Pray et al. 2020

1

1

6

5

--

--

--

USA

School Retreat

Fong et al. 2020

2

3

--

--

3

--

--

Hong Kong

Household

Pitman-Hunt et al. 2021f

2

1

--

--

0

--

--

USA

Household

Teherani et al. 2020

7

4

0

6

10

0

10

USA

Household

Okarska-Napierala, Mańdziuk, and Kuchar 2021

7

3

1

--

9

0

--

Poland

Nursery

Maltezou et al. 2020g

61

1

--

--

1

4

--

Greece

Household

Heudorf, Steul, and Gottschalk 2020

3

2

--

--

1

--

--

Germany

Household

Ji et al. 2020

2

1

--

--

4

--

--

China

Household

Lin et al. 2020h

2

0

0

1

1

0

3

China

Household

Yung et al. 2021

2

0

42

--

--

--

--

Singapore

School

Buonsenso, Danilo, and Graglia 2021

2

9

0

0

--

--

--

Italy

School

Cesilia et al. 2021

1

3

0

0

1

0

1

Indonesia

Household

Gillespie et al. 2021i

1

3

--

--

0

--

--

USA

Household and School

Shah, Kondre and Mavalankar 2021j

72

0

--

--

2

--

--

India

Household

Siegel et al. 2021k

1

12

--

--

2

--

--

USA

School

Brandal et al. 2021

13

2

--

--

1

--

--

Norway

School

Dawson et al. 2021l

1

1

--

--

0

--

--

USA

School

Lin et al. 2021

1

--

--

--

3

--

--

China

Household

Fiel-Ozores et al. 2021

1

--

--

--

1

--

--

Spain

Household

Gupta et al. 2021m

19

0

--

6

7

--

50

India

Household

Hershow et al. 2021n

40

4

--

--

1

--

--

USA

School

Gold et al. 2021o

1

2

--

--

--

--

--

USA

School

Soriano-Arandes et al. 2021

80

60

--

--

107

--

--

Spain

Household

Jordan et al. 2021

30

11

--

--

1

--

--

Spain

School

Abbas and Tornhage 2021

1

2

0

0

1

0

0

Sweden

Household

Lewis et al. 2021

1

1

--

--

2

--

--

USA

Household

Ismail et al. 2021

21

6

--

--

33

--

--

UK

School

Danis et al. 2020p

1

--

--

--

--

--

--

France

School

  1. a: Transmission only reported on 6 of 137 index patients
  2. b: Transmission only reported on 1 of 107 index patients
  3. c: Transmission only reported on 1 of 2 index patients; other index patient self-isolated and had no contacts
  4. d: total of 29 child and adult patients who were exposed but asymptomatic
  5. e: index patient tested “negative” but likely testing error
  6. f: reported household positive cases were excluded as pattern of transmission was not specified
  7. g: concomitant COVID infections of 2 siblings but one tested first and was used as the index patient
  8. h: Neonatal transmission was excluded. Child testing positive was asymptomatic.
  9. i: School A was not included as index patient’s age was unknown
  10. j: Study also reports 3 total positive secondary cases (age unknown) out of 278 total contacts
  11. k: Total of 16 cases (unknown age) out of 320 contacts
  12. l: Total of 1 case out of 102 tested contacts
  13. m: Total of 9 cases (unknown age) out of 122 contacts
  14. n: Data of tertiary transmission was excluded as secondary index patients were not specified
  15. o: Other transmission clusters excluded as index patient was not specified
  16. p: Total of 1 case (unknown age) out of 172 contact