Association of fish oil containing lipid emulsions with retinopathy of prematurity: a retrospective observational study

Table 3 Comparison of erythrocyte fatty acids before and after administration of lipid emulsions in preterm infants

Variables	Before PN		After 14 d of PN
Variables	Group with soy oil emulsions (n=46)	Group with fish oil emulsions (n=43)	Group with soy oil emulsions (n=46)	P value*	Group with fish oil emulsions (n=43)	P value*
Total SFAs	55.98±5.87	55.10±6.32	50.98±2.82	0.000	53.30±6.05	0.257
C16:0	35.88±3.87	35.44±4.24	32.98±1.94	0.001	34.15±3.71	0.211
C18:0	20.10±2.25	19.66±2.38	18.01±1.28	0.000	19.15±2.49	0.411
Total MUFAs	16.92±2.50	17.20±2.04	18.14±2.44	0.052	18.31±2.38	0.032
C16:1n-9	1.03±0.44	1.25±0.43	0.97±0.43	0.589	0.95±0.37	0.004
C18:1n-9	15.88±2.66	15.95±2.14	17.17±2.42	0.049	17.36±2.30	0.049
Total n-6 PUFAs	20.10±5.38	21.16±5.24	24.45±2.77	0.001	21.23±5.01	0.830
C18:2n-6	5.01±2.74	5.85±2.91	9.70±2.74	0.000	7.40±3.36	0.102
C18:3n-6	0.21±0.06	0.20±0.05	0.19±0.05	0.850	0.19±0.06	0.478
C20:4n-6	14.49±4.73	14.60±4.79	14.35±2.97	0.827	13.23±4.30	0.135
C22:5n-6	0.39±0.20	0.51±0.18	0.21±0.17	0.221	0.41±0.20	0.395
Total n-3 PUFAs	7.05±1.28	6.58±1.32	6.49±1.45	0.073	7.18±1.87	0.026
C18:3n-3	2.80±0.38	2.55±0.42	2.51±0.79	0.206	2.38±0.80	0.285
C20:5n-3	2.42±0.62	2.33±0.71	2.47±0.65	0.599	2.42±0.77	0.460
C22:6n-3	1.83±0.73	1.71±0.48	1.52±0.64	0.103	2.37±0.55	0.031
n-6/n-3 PUFAs	2.85±0.69	3.21±0.59	3.77±1.24	0.004	2.96±1.73	0.093
AA/DHA	7.93±4.71	8.54±2.38	9.46±2.53	0.137	5.57±2.18	0.047
n-3 index	4.25±1.08	4.04±1.21	3.98±1.16	0.062	4.79±1.09	0.037

PN Parenteral nutrition. ^*Compared to the same lipid emulsions before PN administration

ISSN: 1471-2431