Physical fitness, physical activity and adiposity: associations with risk factors for cardiometabolic disease and cognitive function across adolescence

Table 5 Cross-sectional associations between physical fitness, physical activity and waist circumference and risk factors of cardiometabolic disease, when controlling for year group and sex. Coefficients (β) are presented in their unstandardised forms, unless otherwise stated, with 95% confidence intervals

Dependent Variables	MSFT		Average Acceleration		Intensity Gradient		Waist Circumference
Dependent Variables	β (95% CI)	p	β (95% CI)	p	β (95% CI)	p	β (95% CI)	p
Systolic Blood Pressure (mmHg)	-0.004 (-0.008, 0.008)	0.106	-0.83 (-1.39, -0.29)	0.005	-19.10 (-30.68, -7.44)	0.002	0.32 (0.02, 0.61)	0.038
Diastolic Blood Pressure (mmHg)	-0.002 (-0.004, 0.0003)	0.222	-0.41 (-0.77, -0.04)	0.031	-6.84 (-14.50, 0.83)	0.084	-0.02 (-0.20, 0.15)	0.815
Mean Arterial Pressure (mmHg)	-0.03 (-0.06, -0.001)	0.113	-0.55 (-0.90, -0.19)	0.004	-10.92 (-18.45, -3.40)	0.006	0.09 (-0.10, 0.27)	0.377
Blood Glucose (mmol·L⁻¹)	-0.0015 (-0.004, 0.001)	0.118	-0.01 (-0.04, 0.02)	0.488	-0.10 (-0.74, 0.56)	0.785	0.01 (-0.01, 0.02)	0.649
Plasma Insulin (pmol·L⁻¹)	-0.003 (-0.18, 0.17)	0.971	0.05 (-1.56, 1.66)	0.951	-24.70 (-57.70, 8.28)	0.146	0.70 (-0.19, 1.59)	0.125
HOMA-IR (AU)	-0.002 (-0.007, 0.004)	0.484	-0.02 (-0.07, 0.04)	0.555	-0.93 (-1.99, 0.13)	0.091	0.02 (-0.01, 0.05)	0.115
IL-6^a	0.15 (-0.14, 0.44)	0.367	-0.60 (-11.63, 11.81)	0.712	-6.20 (-50.97, 79.46)	0.846	1.31 (-0.27, 2.91)	0.093
IL-10^a	0.09 (-0.15, 0.33)	0.462	0.40 (-1.75, 2.59)	0.711	16.42 (-26.26, 83.80)	0.515	0.80 (-0.18, 1.80)	0.162
IL-15^a	0.30 (0.07, 0.54)	0.038	-0.70 (-2.45, 1.09)	0.421	17.35 (-18.98, 69.97)	0.402	-0.40 (-1.37, 0.58)	0.359
IL-1β^a	0.45 (-0.14, 1.04)	0.061	2.33 (-1.80, 6.63)	0.280	12.64 (-51.13, 159.60)	0.780	0.60 (-1.39, 2.63)	0.557

MSFT, Multi-Stage Fitness Test CI, Confidence Interval HOMA-IR, Homeostatic Model Assessment of Insulin Resistance IL, Interleukin
Coefficient and CI are presented as a 1-unit change in the dependent variable for a 1-unit change in MSFT (15 m), average acceleration (1 mg), intensity gradient (1 AU), waist circumference (1 cm)
^adependent variable is log transformed. For log transformed data, the coefficient and CI are presented as the % change for a 1-unit change in the predictor variables (MSFT, average acceleration, intensity gradient and waist circumference)
Significant associations are highlighted in bold (p < 0.05)

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