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Table 1 Clinical and Molecular Characteristics of SickKids cohort with PLGG

From: Clinical and economic impact of molecular testing for BRAF fusion in pediatric low-grade Glioma

 

All

(N = 363)

KIAA1549-BRAF fusion (N = 130)

No Fusion

(N = 233)

Age in years at diagnosis, mean (range)

9.8 (0.2–18.5)

9.0 (0.3–17.7)

10.2 (0.2–18.5)

Fused, %

35.81

100.00

0.00

Female, %

49.58

54.62

46.67

Follow up in years, mean (range)

   

mortality outcome

8.9 (0.0–30.1)

7.7 (0.0–29.4)

9.6 (0.1–30.1)

progression outcome

5.3 (0.0–22.8)

4.7 (0.0–21.6)

5.6 (0.0–22.8)

Died, N (%)

19 (5.23)

3 (2.31)

16 (6.87)

Progressed, N (%)

113 (31.13)

35 (26.92)

78 (33.48)