Table 2 Subgroup analysis of pooled AUC values with 95%CI in pediatric population
Subgroup (N of studies) | Hypertension | Subgroup (N of studies) | Elevated blood pressure | ||||||
|---|---|---|---|---|---|---|---|---|---|
Boys | Girls | Boys | Girls | ||||||
AUC(95%CI) | I2(%) | AUC(95%CI) | I2(%) | AUC(95%CI) | I2(%) | AUC(95%CI) | I2(%) | ||
Region | Region | ||||||||
Asia | Asia | ||||||||
BMI (n = 9) | 0.67 (0.63,0.72) | 93.1 | 0.68 (0.63,0.74) | 92.5 | BMI (n = 4) | 0.68 (0.60,0.76) | 98.8 | 0.64 (0.62,0.67) | 84.7 |
WC (n = 8) | 0.67 (0.61,0.73) | 94.1 | 0.68 (0.62,0.74) | 94.3 | WC (n = 4) | 0.66 (0.58,0.76) | 99.2 | 0.63 (0.60,0.66) | 88.9 |
WHtR (n = 9) | 0.67 (0.62,0.71) | 91.4 | 0.66 (0.61,0.72) | 93.6 | WHtR (n = 4) | 0.66 (0.60,0.73) | 98.5 | 0.62 (0.59,0.65) | 89.0 |
Europe | Europe | ||||||||
BMI (n = 4) | 0.73 (0.64,0.82) | 93.1 | 0.70 (0.63,0.77) | 90.9 | BMI (n = 2) | 0.65 (0.59,0.72) | 91.0 | 0.62 (0.60,0.64) | 0.0 |
WC (n = 4) | 0.72 (0.64,0.81) | 91.9 | 0.68 (0.62,0.74) | 83.4 | WC (n = 1) | 0.61 (0.58,0.64) | – | 0.61 (0.58,0.64) | – |
WHtR (n = 4) | 0.66 (0.55,0.79) | 95.5 | 0.65 (0.58,0.73) | 89.8 | WHtR (n = 2) | 0.64 (0.60,0.69) | 83.0 | 0.61 (0.59,0.64) | 0.0 |
America | America | ||||||||
BMI (n = 3) | 0.66 (0.57,0.76) | 95.1 | 0.77 (0.55,1.00) | 98.9 | – | – | – | – | – |
WC (n = 3) | 0.71 (0.57,0.90) | 96.9 | 0.75 (0.52,1.00) | 99.4 | – | – | – | – | – |
WHtR (n = 3) | 0.69 (0.54,0.88) | 96.4 | 0.73 (0.52,1.00) | 98.7 | – | – | – | – | – |
Hypertension criterion | Elevated blood pressure criterion | ||||||||
≥90th percentile | ≥90th percentile | ||||||||
BMI (n = 4) | 0.68 (0.63,0.74) | 90.8 | 0.77 (0.66,0.91) | 93.6 | BMI (n = 1) | 0.56 (0.54,0.59) | – | 0.59 (0.56,0.62) | – |
WC (n = 4) | 0.72 (0.64,0.82) | 89.9 | 0.75 (0.61,0.93) | 91.3 | WC (n = 1) | 0.54 (0.52,0.57) | – | 0.57 (0.54,0.60) | – |
WHtR (n = 4) | 0.72 (0.64,0.80) | 84.4 | 0.75 (0.64,0.87) | 93.6 | WHtR (n = 1) | 0.56 (0.54,0.59) | – | 0.56 (0.53,0.59) | – |
≥95th percentile | ≥95th percentile | ||||||||
BMI (n = 12) | 0.68 (0.64,0.74) | 96.9 | 0.68 (0.64,0.72) | 94.5 | BMI (n = 5) | 0.69 (0.63,0.75) | 97.9 | 0.64 (0.62,0.66) | 65.1 |
WC (n = 11) | 0.68 (0.63,0.73) | 96.7 | 0.67 (0.63,0.71) | 93.7 | WC (n = 4) | 0.68 (0.60,0.77) | 99.0 | 0.64 (0.62,0.66) | 74.8 |
WHtR (n = 12) | 0.65 (0.61,0.70) | 94.9 | 0.64 (0.61,0.68) | 92.9 | WHtR (n = 5) | 0.68 (0.63,0.73) | 97.3 | 0.63 (0.62,0.65) | 49.1 |
Hypertension diagnosis basis | Elevated blood pressure diagnosis basis | ||||||||
NHBPEP | NHBPEP | ||||||||
BMI (n = 8) | 0.69 (0.63,0.75) | 97.6 | 0.67 (0.62,0.73) | 94.1 | BMI (n = 4) | 0.69 (0.62,0.77) | 98.5 | 0.65 (0.63,0.67) | 68.7 |
WC (n = 7) | 0.67 (0.60,0.74) | 97.5 | 0.65 (0.61,0.70) | 91.3 | WC (n = 4) | 0.68 (0.60,0.77) | 99.0 | 0.64 (0.62,0.66) | 74.8 |
WHtR (n = 8) | 0.64 (0.59,0.70) | 94.7 | 0.64 (0.59,0.68) | 91.9 | WHtR (n = 4) | 0.68 (0.62,0.74) | 98.0 | 0.64 (0.63,0.65) | 32.0 |
Other local criteria of hypertension | Other local criteria of elevated blood pressure | ||||||||
BMI (n = 8) | 0.68 (0.62,0.74) | 94.0 | 0.73 (0.65,0.82) | 96.5 | BMI (n = 2) | 0.62 (0.51,0.75) | 97.5 | 0.60 (0.57,0.62) | 0.0 |
WC (n = 8) | 0.71 (0.65,0.77) | 93.8 | 0.73 (0.63,0.84) | 98.2 | WC (n = 1) | 0.54 (0.52,0.57) | – | 0.57 (0.54,0.60) | – |
WHtR (n = 8) | 0.70 (0.64,0.76) | 92.3 | 0.71 (0.63,0.80) | 96.6 | WHtR (n = 2) | 0.61 (0.51,0.73) | 96.7 | 0.58 (0.54,0.63) | 73.7 |
BP measurement device | BP measurement device | ||||||||
Mercury sphygmomanometer | Mercury sphygmomanometer | ||||||||
BMI (n = 9) | 0.66 (0.62,0.71) | 93.6 | 0.70 (0.63,0.77) | 95.2 | BMI (n = 4) | 0.68 (0.60,0.76) | 98.8 | 0.64 (0.62,0.67) | 84.7 |
WC (n = 9) | 0.67 (0.61,0.73) | 93.8 | 0.68 (0.60,0.78) | 97.9 | WC (n = 4) | 0.66 (0.58,0.76) | 99.2 | 0.63 (0.60,0.66) | 88.9 |
WHtR (n = 9) | 0.66 (0.62,0.71) | 90.3 | 0.66 (0.60,0.73) | 94.5 | WHtR (n = 4) | 0.66 (0.60,0.73) | 98.5 | 0.62 (0.59,0.65) | 89.0 |
Automated BP monitor | Automated BP monitor | ||||||||
BMI (n = 7) | 0.72 (0.64,0.80) | 97.9 | 0.71 (0.64,0.79) | 96.8 | BMI (n = 2) | 0.65 (0.59,0.72) | 91.0 | 0.62 (0.60,0.64) | 0.0 |
WC (n = 6) | 0.72 (0.64,0.81) | 98.1 | 0.71 (0.63,0.80) | 97.2 | WC (n = 1) | 0.61 (0.58,0.64) | – | 0.61 (0.58,0.64) | – |
WHtR (n = 7) | 0.68 (0.60,0.76) | 97.3 | 0.68 (0.61,0.77) | 96.9 | WHtR (n = 2) | 0.64 (0.60,0.69) | 83.0 | 0.61 (0.59,0.64) | 0.0 |