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Table 2 Clinical features of documented neurological manifestation with RSV confirmed infection at time of admission

From: Clinical features of respiratory syncytial virus bronchiolitis in an infant: rapid and fatal brain involvement

Source, y

Age / Sex

Clinical picture at time of admission

CNS involvement at time of admission

Diagnosis of RSV infection

Outcome

Xu L et al., 2018 [14]

2 years / F

Respiratory and cardiac arrest

extensive

brain edema

Antigen rapid test

Death for multiple organ failure

Morichi et al., 2011 [15]

1 year / M

CHARGE syndrome

involuntary movements, impaired consciousness

RT-LAMP

Survived with mental retardation

11 months / F

N/A

status epilepticus, impaired consciousness

RT-LAMP

Survived with mental retardation

3 years / M

N/A

generalized tonic-clonic seizure

RT-LAMP

Survived

1 year / F

N/A

generalized tonic-clonic seizure

RT-LAMP

Survived

3 years / M

N/A

Nuchal rigidity

RT-LAMP

Survived

10 days / M

N/A

generalized tonic-clonic seizure

RT-LAMP

Survived

4 months / M

cardiopulmonary arrest

status epilepticus, impaired consciousness

RT-LAMP

Survived with mental retardation

27 days / M

respiratory failure

impaired consciousness, convulsions

RT-LAMP

Survived with mental retardation

14 days / F

Apnea

lethargy

RT-LAMP

N/A

Otake et al., 2007 [16]

11 months / M

Fever, cough

generalized tonic-clonic seizure

Antigen rapid test

N/A

Zlateva et al., 2004 [17]

4 months / M

Fever, cough, tachycardia

convulsions

RT-PCR

Survived

Present report

40 days / M

Dyspnea

none

RT-PCR

Death for multiple organ failure

  1. N/A data not available, RT-LAMP Reverse transcription loop-mediated isothermal amplification, RT-PCR Reverse transcriptase-polymerase chain reaction