Fatigue in children and adolescents perinatally infected with human immunodeficiency virus: an observational study

Table 1 Demographics of Perinatally Human Immunodeficiency Virus infected (PHIV+) children and HIV uninfected (HIV-) matched controls

Characteristics	n	PHIV+	n	HIV-	P^a
Number of participants		14		14
Male sex	14	5 (35.7%)	14	7 (50.0%)	0.710
Age, y, median (IQR)	14	10.2 (9.2–11.4)	14	10.0 (8.1–11.5)	0.571
Region of birth	14		14		0.174
Asia		1		0
Sub-Sahara Africa		13		10
Eastern Europe		0		2
Central America		0		2
ISCED highest, median (IQR)	13		14		0.248
0-2		2		0
3-5		7		7
6-8		4		7
Number of parents with a job	13		13		0.202
1		6		2
2		7		10
Adopted	14	13 (93%)	14	12 (86%)	0.541
Age at HIV diagnosis (y), median (IQR)	14	2.10 (0.33–3.45)
Perinatal transmission, n (%)	14	14 (100%)
CDC category^a, n (%) N/A	14
N/A		12 (86%)
B		1 (7%)
C		1 (7%)
Nadir CD4+ T-cell z-score^a, median (IQR)	14	−0.76 (−1.35 to −0.13)
Zenith HIV VL (copies/mL) ^a, median (IQR)	14	107,492 (265–296,408)
cART, n (%)	14	14 (100%)
Age at cART initiation (y), median (IQR)	14	3.07 (1.06–5.41)
Duration of cART use (y), mean (SD)	14	6.79 (2.56)
HIV diagnosis to cART initiation (mo), median (IQR)	14	22.92 (4.00–59.38)
Undetectable HIV VL at assessment, n (%)	14	14 (100%)

Values are reported as n (%), unless otherwise stated. Undetectable is defined as HIV RNA < 40c/mL, and allowing viral blips. Values are reported as mean (SD), median (IQR) or n (%). Abbreviations: n Number, PHIV+ Perinatally human immunodeficiency virus infected, HIV− HIV-uninfected controls, y Year, IQR Interquartile range, ISCED International Standard Classification of Education; Centers for Disease Control and Prevention, N Not symptomatic, A, mildly symptomatic; B, moderately symptomatic; C, severely symptomatic, VL Viral load, mL Milliliter, cART Combination antiretroviral therapy, SD Standard deviation, mo Month
^aSince registration in the Netherlands

ISSN: 1471-2431