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Table 2 Demographic, clinical and laboratory characteristics of child survivors vs. non-survivors included in the MISCO Study

From: Mortality and clinical characteristics of multisystem inflammatory syndrome in children (MIS-C) associated with covid-19 in critically ill patients: an observational multicenter study (MISCO study)

Demographic characteristics

Survivors

n= 71

Non-survivors

n=7

p-valuea

Age < 7 years, n (%)

32(45.1)

5 (71.4)

0.23

Age > 7 years, n (%)

39 (55)

2 (28.6)

 

Nutritional status, n (%)

   

 Obesity

21(31)

2 (28.5)

0.25

 Normal

38 (53.5)

7(100)

0.018

Days in PICU, median (IQR)

11 (6-114)

13(9-65)

0.46

Days from onset of symptoms to admission to PICU (IQR)

5(1-92)

6 (3-12)

0.003b

Skin and mucous membranes, n (%)

   

 Lips/tongue

16 (22.5)

1(14.3)

0.61

 Hand/foot edema

32 (45.1)

2(28.5)

0.46

 Conjunctival injection

23 (32.4)

0

0.09

Gastrointestinal, n(%)

   

 Diarrhea

54 (76.1)

1(14.3)

0.002

 Vomiting

54 (76.1)

4(57.1)

0.36

 Abdominal pain

51 (72)

4(57.1)

0.42

Cardiovascular, n(%)

   

 Shock

61 (86)

7(100)

0.98

 Hypotension

55(77.5)

6(85.7)

0.6

 Arrhythmia

8(11.2)

3(42.9)

0.05

Pericarditis

0

2(28.6)

0.007

Renal, n (%)

   

 Acute kidney injury

17(24)

6(85.7)

<0.001

Ferritin > 500 mcgr/dl, n (%)

32(45)

7(100)

0.012

C-reactive protein > 4 mgr/dl, n (%)

58(82)

4(57)

0.14

Dimero D > 3000 ngr/ml, n(%)

39(55)

5(71)

0.46

Respiratory support, n (%)

   

 NIV

68(96)

0

1.0

 Conventional MV

15 (21.1)

7(100)

<0.001

 HFOV

1 (1.4)

4(57.1)

<0.001

Dialysis (RRT), n(%)

3(4.2)

6(85.7)

<0.001

  1. NIV – noninvasive ventilation. MV – mechanical ventilation. HFOV – high-frequency oscillatory ventilation. RRT – renal replacement therapy. a Fisher-exact test. bMann-Whitney U test