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Table 2 Demographic, clinical and laboratory characteristics of child survivors vs. non-survivors included in the MISCO Study

From: Mortality and clinical characteristics of multisystem inflammatory syndrome in children (MIS-C) associated with covid-19 in critically ill patients: an observational multicenter study (MISCO study)

Demographic characteristics Survivors
n= 71
Non-survivors
n=7
p-valuea
Age < 7 years, n (%) 32(45.1) 5 (71.4) 0.23
Age > 7 years, n (%) 39 (55) 2 (28.6)  
Nutritional status, n (%)    
 Obesity 21(31) 2 (28.5) 0.25
 Normal 38 (53.5) 7(100) 0.018
Days in PICU, median (IQR) 11 (6-114) 13(9-65) 0.46
Days from onset of symptoms to admission to PICU (IQR) 5(1-92) 6 (3-12) 0.003b
Skin and mucous membranes, n (%)    
 Lips/tongue 16 (22.5) 1(14.3) 0.61
 Hand/foot edema 32 (45.1) 2(28.5) 0.46
 Conjunctival injection 23 (32.4) 0 0.09
Gastrointestinal, n(%)    
 Diarrhea 54 (76.1) 1(14.3) 0.002
 Vomiting 54 (76.1) 4(57.1) 0.36
 Abdominal pain 51 (72) 4(57.1) 0.42
Cardiovascular, n(%)    
 Shock 61 (86) 7(100) 0.98
 Hypotension 55(77.5) 6(85.7) 0.6
 Arrhythmia 8(11.2) 3(42.9) 0.05
Pericarditis 0 2(28.6) 0.007
Renal, n (%)    
 Acute kidney injury 17(24) 6(85.7) <0.001
Ferritin > 500 mcgr/dl, n (%) 32(45) 7(100) 0.012
C-reactive protein > 4 mgr/dl, n (%) 58(82) 4(57) 0.14
Dimero D > 3000 ngr/ml, n(%) 39(55) 5(71) 0.46
Respiratory support, n (%)    
 NIV 68(96) 0 1.0
 Conventional MV 15 (21.1) 7(100) <0.001
 HFOV 1 (1.4) 4(57.1) <0.001
Dialysis (RRT), n(%) 3(4.2) 6(85.7) <0.001
  1. NIV – noninvasive ventilation. MV – mechanical ventilation. HFOV – high-frequency oscillatory ventilation. RRT – renal replacement therapy. a Fisher-exact test. bMann-Whitney U test