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Table 4 Binary logistic regression models for the association between the latent methylation factors and emotional symptoms and hyperactivity in 4 years old children

From: Gender-specific associations of pregnancy-related anxiety with placental epigenetic patterning of glucocorticoid response genes and preschooler’s emotional symptoms and hyperactivity

Predictors Emotional Symptoms Hyperactivity
ORa(95%CI) Pa ORa(95%CI) Pa
Boys
 Factor1* 1.64(1.03,2.59) 0.037 1.80(1.15,2.83) 0.011
 Factor2* 1.31(0.78,2.20) 0.300 1.22(0.76,1.95) 0.416
 Factor3* 0.67(0.41,1.10) 0.112 1.04(0.68,1.60) 0.866
 Factor4* 0.53(0.29,0.97) 0.039 0.89(0.57,1.38) 0.597
 Factor5* 0.99(0.68,1.44) 0.936 0.67(0.44,1.03) 0.069
Girls
 Factor1* 1.05(0.69,1.58) 0.829 1.09(0.70,1.69) 0.710
 Factor2* 0.71(0.46,1.09) 0.113 1.35(0.80,2.28) 0.258
 Factor3* 0.94(0.60,1.47) 0.773 0.73(0.44,1.19) 0.206
 Factor4* 1.21(0.79,1.85) 0.385 1.15(0.73,1.82) 0.543
 Factor5* 0.93(0.57,1.52) 0.785 1.05(0.62,1.78) 0.855
  1. Abbreviations: * Latent methylation variables
  2. a represents that these ORs were calculated by binary logistic regression, adjusted by maternal age, pre-pregnancy BMI, gestational weight gain, education, family monthly income, smoking, drinking, gestational diabetes, pregnancy-induced hypertension, delivery mode and exclusive breastfeeding at first 6 months