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Table 4 Binary logistic regression models for the association between the latent methylation factors and emotional symptoms and hyperactivity in 4 years old children

From: Gender-specific associations of pregnancy-related anxiety with placental epigenetic patterning of glucocorticoid response genes and preschooler’s emotional symptoms and hyperactivity

Predictors

Emotional Symptoms

Hyperactivity

ORa(95%CI)

Pa

ORa(95%CI)

Pa

Boys

 Factor1*

1.64(1.03,2.59)

0.037

1.80(1.15,2.83)

0.011

 Factor2*

1.31(0.78,2.20)

0.300

1.22(0.76,1.95)

0.416

 Factor3*

0.67(0.41,1.10)

0.112

1.04(0.68,1.60)

0.866

 Factor4*

0.53(0.29,0.97)

0.039

0.89(0.57,1.38)

0.597

 Factor5*

0.99(0.68,1.44)

0.936

0.67(0.44,1.03)

0.069

Girls

 Factor1*

1.05(0.69,1.58)

0.829

1.09(0.70,1.69)

0.710

 Factor2*

0.71(0.46,1.09)

0.113

1.35(0.80,2.28)

0.258

 Factor3*

0.94(0.60,1.47)

0.773

0.73(0.44,1.19)

0.206

 Factor4*

1.21(0.79,1.85)

0.385

1.15(0.73,1.82)

0.543

 Factor5*

0.93(0.57,1.52)

0.785

1.05(0.62,1.78)

0.855

  1. Abbreviations: * Latent methylation variables
  2. a represents that these ORs were calculated by binary logistic regression, adjusted by maternal age, pre-pregnancy BMI, gestational weight gain, education, family monthly income, smoking, drinking, gestational diabetes, pregnancy-induced hypertension, delivery mode and exclusive breastfeeding at first 6 months