Table 3 Isolated gram-negative pathogens and susceptibility to antibiotics in neonates with suspected antibiotic-resistant neonatal infection admitted to Castor’s neonatal unit (Bangui, CAR) from December 2018 to March 2020
Antibiotic | K.pneumoniae (n = 13) | K.oxytoca (n = 6) | E.coli (n = 7) | All gram-negative bacteria (n = 29) | ||||
|---|---|---|---|---|---|---|---|---|
|  | R/(R + S) | R% | R/(R + S) | R% | R/(R + S) | R% | R/(R + S) | R% |
Beta-lactam | ||||||||
AMP | 13/13 | 100% | 6/6 | 100% | 6/6 | 100% | 27/27 | 100% |
FOX | 1/13 | 7.7% | 2/6 | 33.3% | 1/7 | 14.3% | 5/29 | 17.2% |
CTX | 12/12 | 100% | 5/6 | 83.3% | 3/6 | 50% | 21/27 | 77.8% |
FEP | 12/12 | 100% | 5/6 | 83.3% | 4/7 | 57.1% | 21/28 | 75% |
IPM | 0/12 | 0% | 0/6 | 0% | 0/7 | 0% | 0/28 | 0% |
Non-beta-lactam | ||||||||
GEN | 13/13 | 100% | 4/5 | 80% | 6/7 | 85.7% | 24/28 | 85.7% |
AMK | 0/13 | 0% | 2/6 | 33.3% | 0/7 | 0% | 2/29 | 6.9% |
CAF | 3/12 | 25% | 5/6 | 83.3% | 2/7 | 28.6% | 13/28 | 46.4% |
|  | (R + I)/(R + I + S) | (R + I)% | (R + I)/(R + I + S) | (R + I)% | (R + I)/(R + I + S) | (R + I)% | (R + I)/(R + I + S) | (R + I)% |
CIP | 8/9 | 88.9% | 5/5 | 100% | 4/5 | 80% | 19/22 | 86.4% |