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Table 2 Therapeutic schedule and outcomes of the 13 patients with RMS and bone marrow metastasis

From: Clinical features and prognosis of paediatric rhabdomyosarcoma with bone marrow metastasis: a single Centre experiences in China

Case Treatment Take From onset Main site of Treatment Follow-up Outcome
Temozolomide to progression(m) Progression after relapse (m)
1 CT NO 3 Primate site, lung, intracalvarium CT 6 death
2 CT + ST NO 6 Primate site,lung,intracalvarium CT 8 death
3 CT + RT + ST NO 6 Intracalvarium CT + TT 8 death
4 CT + RT + ST NO 15 Primary site, Lymph node CT 27 death
5 CT + RT + ST NO 13.5 Intracalvarium CT + ST + RT + CART 36.5 death
6 CT + RT Yes 4.3 Intracalvarium CT 8 death
7 CT + RT + ST Yes 4.8 Lung, bone marrow CT 16 death
8 CT + RT + ST Yes 9 Bone marrow, Intracalvarium CT + ST + RT + TT 12.3 death
9 CT + RT + ST Yes 19 Bone CT + RT 21 Survive
10 CT + RT + ST Yes 21.2 Primary site, lymph nodes CT + ST + RT 27.2 survive
11 CT + RT + ST Yes 12 Lymph nodes CT + ST + RT 27. 6 survive
12 CT + RT + ST Yes 28.3 Primary site CT + ST + RT + TT 46.2 survive
13 CT + RT + ST Yes / / / 14.5 survive
  1. Abbreviations: CT Chemotherapy, RT Radiotherapy, ST Surgery treatment, CAR-T Chimeric Antigen Receptor T-Cell Immunotherapy, TT Targeted treatment