Skip to main content

Table 1 Clinical features of 46 Chinese CF patients at the time of diagnosis

From: Prognosis and treatment of 46 Chinese pediatric cystic fibrosis patients

Variables N = 46
Sex –no (%) 46
 Female - no (%) 20 (43.48%)
 Male - no (%) 26 (56.52%)
Age of onset of symptoms -year 4.05 ± 3.77 (0–12, median2.50)
Age at diagnosis -year 8.05 ± 4.26 (0.59–15.88, median 8.74)
Diagnostic delay -year 4.01 ± 3.72 (0.14–12.44, median 3.05)
Pulmonary symptoms
 Cough -no/total no (%) 46/46 (100.00)
 Wheezing -no/total no (%) 12/46 (26.09)
Extra pulmonary symptoms 3/46 (6.52)
Respiratory infection times 4.49 ± 2.13
Pancreatic malfunction –no/total no (%) 18/46 (39.13)
ABPA -no/total no (%) 14/46 (30.43)
Asthma -no/total no (%) 10/46 (21.74)
Lung function -no/total no (%) 31/46 (67.39)
 FEV1 75.44% ± 22.40% (25.1–118.2%,74.5%)
 FVC 83.59% ± 16.99% (33.1–113.9%,86.1%)
 FEF75 39.45% ± 26.68%(6.6–112.9%,33.3%)
Bacterial colonies n (%) -no/total no (%) 46/46 (100.00)
 PA -no/total no (%) 33/46 (71.74)
 SA -no/total no (%) 9/46 (19.57)
CT scan 46/46 (100.00)
 Bronchiectasis -no/total no (%) 42/46 (91.30)
 Only Inflammation -no/total no (%) 4/46 (8.70)
 Mucus plugging -no/total no (%) 14/46 (30.43)
 Pleural thickening -no/total no (%) 14/46 (30.43)
  1. Plus–minus values are means ± SD.
  2. ABPA Allergic bronchopulmonary aspergillosis, PA Pseudomonas aeruginosa, SA Staphylococcus aureus. Normal/mild disease: FEV1 > 70% predicted, Moderate obstruction: FEV1 ranges from 40 to 69% predicted, Severe disease: FEV1 less than 40% [10].