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Table 1 Clinical features of 46 Chinese CF patients at the time of diagnosis

From: Prognosis and treatment of 46 Chinese pediatric cystic fibrosis patients

Variables

N = 46

Sex –no (%)

46

 Female - no (%)

20 (43.48%)

 Male - no (%)

26 (56.52%)

Age of onset of symptoms -year

4.05 ± 3.77 (0–12, median2.50)

Age at diagnosis -year

8.05 ± 4.26 (0.59–15.88, median 8.74)

Diagnostic delay -year

4.01 ± 3.72 (0.14–12.44, median 3.05)

Pulmonary symptoms

 Cough -no/total no (%)

46/46 (100.00)

 Wheezing -no/total no (%)

12/46 (26.09)

Extra pulmonary symptoms

3/46 (6.52)

Respiratory infection times

4.49 ± 2.13

Pancreatic malfunction –no/total no (%)

18/46 (39.13)

ABPA -no/total no (%)

14/46 (30.43)

Asthma -no/total no (%)

10/46 (21.74)

Lung function -no/total no (%)

31/46 (67.39)

 FEV1

75.44% ± 22.40% (25.1–118.2%,74.5%)

 FVC

83.59% ± 16.99% (33.1–113.9%,86.1%)

 FEF75

39.45% ± 26.68%(6.6–112.9%,33.3%)

Bacterial colonies n (%) -no/total no (%)

46/46 (100.00)

 PA -no/total no (%)

33/46 (71.74)

 SA -no/total no (%)

9/46 (19.57)

CT scan

46/46 (100.00)

 Bronchiectasis -no/total no (%)

42/46 (91.30)

 Only Inflammation -no/total no (%)

4/46 (8.70)

 Mucus plugging -no/total no (%)

14/46 (30.43)

 Pleural thickening -no/total no (%)

14/46 (30.43)

  1. Plus–minus values are means ± SD.
  2. ABPA Allergic bronchopulmonary aspergillosis, PA Pseudomonas aeruginosa, SA Staphylococcus aureus. Normal/mild disease: FEV1 > 70% predicted, Moderate obstruction: FEV1 ranges from 40 to 69% predicted, Severe disease: FEV1 less than 40% [10].