Interaction between antibiotic use and MS4A2 gene polymorphism on childhood eczema: a prospective birth cohort study

Table 1 Candidate genes and SNPs analyzed in this study

Gene	SNP	Chromosome position	Location	Allele ^a	MAF ^b
IL13	rs20541	5:132660272	Exon 4	G/A	0.34/0.20/0.20
IL4	rs2243250	5:132673462	Promoter	T/C	0.21/T, 0.15/0.36 ^c
MS4A2	rs1441586	11:60088555	Promoter	T/C	0.35/0.44/0.49
MS4A2	rs569108	11:60095631	Exon7	A/G	0.18/0.03/0.17
IL4RA	rs1805010	16:27344882	Exon 5	A/G	0.50/0.45/0.48
IL4RA	rs1801275	16:27363079	Exon 12	A/G	0.18/0.20/A, 0.34 ^d

SNP single-nucleotide polymorphism, MAF minor allele frequency
^a Major/minor allele shown
^b MAF in this study/Europeans/Africans. MAF in Europeans and Africans was from National Center for Biotechnology Information (https://www.ncbi.nlm.nih.gov/)
^c Minor allele is C in this study and Africans, but it is T in Europeans
^d Minor allele is G in this study and Europeans, but it is A in Africans

ISSN: 1471-2431