A pilot study to evaluate the role of circulation CD4+ CCR6+ CRTh2+ cell in predicting risk of asthma in wheezing children

Table 2 Comparison of risk factors according to asthma outcome in wheezing children

Variables	Study group (43)
Variables	Non-asthma	Asthma	p value
Total n(%)	17(39.5)	26(60.5)
Sex n(%)
Male	10(58.8)	19(73.1)	0.329^*
Female	7 (41.2)	7(26.9)	0.329^*
Age group n(%)
≤3 years old	10(58.8)	11(42.3)	0.289^*
3-5 years old	7(41.2)	15(57.7)	0.289^*
Systemic glucocorticoid n(%)
Yes	6(35.3)	4(15.4)	0.254^*
No	11(64.7)	22(84.6)	0.254^*
Wheezing frequency n(%)
<4 times	13(76.5)	8(30.8)	0.003^*
≥4 times	4(23.5)	18(69.2)	0.003^*
Age when first wheezing n(%)
≤3 years old	17(100.0)	21(80.8)	0.139^*
3-5years old	0(0.0)	5(19.2)	0.139^*
Duration of wheezing onset to enroll, median (IQR)(years)	0.9(0.0,1.5)	2.1(0.4, 4.8)	0.052^**
Allergic rhinitis n(%)	7(41.2)	15(57.7)	0.289^*
Atopic dermatitis n(%)	9(52.9)	17(65.4)	0.415^*
Family allergic diseases	6(35.3)	17(65.4)	0.053^*
Asthma prediction index n(%)	9(52.9)	23(88.5)	0.024^***
Inhalant allergen sIgE n(%)	8(47.1)	16(69.6)	0.151^*
Food allergen sIgE n(%)	8(47.1)	15(65.2)	0.251^*
Total IgE(IU/ml)	46(8.6, 204.0)	192.5(60.9, 805.0)	0.055^**
CD4⁺CCR6⁺CRTh2⁺cells mean±SD(%)	0.8±0.6	1.6±0.8	<0.001^**

*: Pearson Chi-Square; **: Mann-Whitney Rank sum test; **: t-test; ***: Continuity Correction

ISSN: 1471-2431