Skip to main content

Table 4 Treatment

From: COVID-19 related multisystem inflammatory syndrome in children (MIS-C): a case series from a tertiary care pediatric hospital in Qatar

  Case-1 Case-2 Case-3 Case-4 Case-5 Case-6 Case-7 Summary
IVIG 2 g/kg;
1 dose
1 g/kg;
1 dose
2 g/kg;
2 dose
1.5 g/kg;
1 dose
2 g/kg;
1 dose
2 g/kg;
2 dose
2 g/kg;
2 dose
100%
aCorticosteroids Prednisolone (2 mg/kg/D;1 M) Prednisolone (2 mg/kg/D; 2 W) None Methylprednisolone (30 mg/kg/D; 3D)
Prednisolone (1 mg/kg/day; 1 M)
Methylprednisolone (30 mg/kg/D; 1 dose)
Prednisolone
2 mg/kg/day; 6 W)
Methylprednisolone (30 mg/kg/D; 3D)
Prednisolone
2 mg/kg/day; 3 M)
Prednisolone (2 mg/kg/D; 3 M) 85.7%
Antibiotics FEP (2D)
MEM (5D) VAN(3D) AMC (7D)
CRO (7D)
CLI (7D)
CRO (5D) CRO (3D)
MTZ (4D)
MEM (1D)
TZP (5D)
CRO (2D) None 100%
Anticoagulants Enoxaparin
(2 mg/kg/D;
3D)
Enoxaparin
(2 mg/kg/D;
15D)
None Enoxaparin
(2 mg/kg/D;
15D)
Enoxaparin
(1 mg/kg/D;
4D)
Enoxaparin
(1 mg/kg;
2 dose)
Enoxaparin
(2 mg/kg/D; 6 M) Clopidogrel (10 mg/D; 6 M)
Warfarin
(2 mg/cont.)
85.7%
Epinephrine/ norepinephrine EPI (0.1 μg/kg/min, 2D)
N-EPI (0.1 μg/kg/min, 4D)
N-EPI (0.15 μg/kg/min, 2D) None N-EPI
(0.05 μg/kg/min, 4D)
None N-EPI (0.1 μg/kg/min, 1D) None 42.9%
Aspirin 4 mg/kg/D; 1 M 5 mg/kg/D; 1 M 5 mg/kg/D; 3 M Yes 2 mg/kg/D; continued 3 mg/kg/D; 3 M 5 mg/kg/D; continued 100%
aInterleukin-1ra inhibitor None None None Anakinra
(5 mg/kg/D; 2 M)
None None Anakinra (4 mg/kg/D, 2 M) 28.6%
  1. aduration includes tapering
  2. M month; W week; D day; IVIG intravenous immunoglobulin; AMC amoxicillin-clavulanic acid; MEM meropenem; FEP cefepime; CRO ceftriaxone; CLI clindamycin; TZP piperacillin-tazobactam; EPI epinephrine; N-EPI norepinephrine