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Table 2 Comparison of standardized scores in each domain of guidelines and subgroups by AGREE II

From: Quality of pediatric clinical practice guidelines

Subject Scope and purpose a Stakeholder involvement a Rigor of development a Clarity of presentation a Applicability a Editorial independence a Overall assessment a Recommend b Recommend with modification b Not recommend b
Overall 55.16% 34.22% 28.62% 66.77% 21.26% 35.26% 4.26 6.48% 69.91% 23.61%
Country/ Region
 Developed 57.59% 35.79% 28.70% 68.32% 22.85% 38.37% 4.78 6.25% 77.08% 16.67%
 Developing 52.11% 32.26% 28.53% 65.53% 19.27% 31.38% 4.12 5.00% 64.17% 30.83%
p 0.001** 0.080 0.943 0.144 0.060 0.023* 0.052 0.055
Organization/ Group
 Yes 55.67% 34.32% 28.98% 68.35% 22.26% 34.93% 4.36 6.49% 72.43% 21.08%
 No 52.15% 33.60% 26.51% 57.35% 15.26% 37.23% 3.65 3.23% 54.84% 41.93%
p 0.083 0.801 0.470 < 0.001** < 0.001** 0.595 < 0.001** 0.009
Evidence based
 Yes 56.41% 35.75% 31.88% 69.00% 22.70% 35.98% 4.48 7.41% 75.31% 17.28%
 No 51.39% 29.63% 18.85% 60.08% 16.94% 33.10% 3.59 1.85% 53.70% 44.45%
p 0.008** < 0.001** < 0.001** < 0.001** 0.001** 0.358 < 0.001** < 0.001
  1. AGREE II The Appraisal of Guidelines for Research and Evaluation II; a Continuous variable is presented as mean; b Categorical variable is reported as percentage; *p < 0.05 (two-sample t-test); **p < 0.01 (two-sample t-test); p < 0.01 (Person’s x2 test)