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Table 2 Comparison of biochemical parameters between SOB and NAFLD

From: Clinical characteristics and risk factors of nonalcoholic fatty liver disease in children with obesity

Groups

SOB

NAFLD

F/Z

p-value

SS

NASH

ALT (U/L)

17 (9)ab

26 (21)a

106 (41)

161.92

0.001

AST (U/L)

22 (8)ab

26 (14)a

62 (26)

112.41

0.001

Uric acid (μmol/L)

352 (96)ab

406 (124)a

455 (141)

49.96

0.001

Triglycerides (mmol/L)

1.05 (0.62)ab

1.37 (0.91)

1.31 (0.90)

16.83

0.001

Cholesterol (mmol/L)

4.25 ± 0.99a

4.33 ± 0.89

4.59 ± 0.88

2.29

0.103

HDL (mmol/L)

1.27 (0.37)b

1.17 (0.36)

1.18 (0.30)

18.23

0.001

Fasting glucose (mmol/L)

4.73 ± 0.44b

4.61 ± 0.48

4.61 ± 0.59

3.08

0.047

Fasting insulin (mU/L)

12.71 (12.08)a

15.01 (14.39)a

21.30 (7.60)

12.39

0.002

HOMA-IR

2.77 (2.53)a

3.06 (3.00)a

4.2 (4.61)

10.39

0.006

  1. vs. NASH group, a p < 0.001; vs. SS group, b p < 0.001. Normal distribution data are expressed as the mean ± SD. Non-normal distribution data are presented as median (interquartile)
  2. SOB Simple Obese, NAFLD Nonalcoholic Fatty Liver Disease, SS Simple Steatosis, NASH Nonalcoholic Fatty Hepatitis, ALT Alanine aminotransferase, AST Aspartate aminotransferase, HDL High-density lipoprotein, HOMA-IR Homeostasis model assessment of insulin resistance