Table 1 The clinical and imaging characteristics of 64 patients with KHE
From: Kaposiform haemangioendothelioma: magnetic resonance imaging features in 64 cases
Parameters | Age at discovery of tumor lesion <6 (m) | Age at discovery of tumor lesion ≥6 (m) | Total | P-values |
|---|---|---|---|---|
n = 36 | n = 28 | n = 64 | ||
Patients clinical characteristics | ||||
Sex | ||||
Male | 24 (66.7%) | 18 (64.2%) | 42 (65.6%) | 0.842 |
Female | 12 (33.3%) | 10 (35.7%) | 22 (34.4%) | - |
Lesions types | ||||
Superficial | 11 (30.6%) | 5 (17.9%) | 16(25.0%) | 0.244 |
Mixed | 25 (69.4%) | 13 (46.4%) | 38(59.4%) | 0.063 |
Deep | - | 10 (35.7%) | 10(15.6%) | <0.001 |
KMP* | ||||
With | 23(63.9%) | 4 (14.3%) | 27(42.2%) | <0.001 |
Without | 13(36.1%) | 24(85.7%) | 37(57.8%) | - |
Musculoskeletal complication | 17(47.2 %) | 20 (71.4%) | 37 (57.8%) | 0.052 |
Chronic pain | - | 4(14.3%) | 4(6.2%) | 0.019 |
Decreased range of motion | 17(47.2%) | 18(64.3%) | 35(54.7%) | 0.174 |
Physical deformity | - | 8(28.6%) | 8(12.5%) | 0.001 |
Skin lesion | ||||
With | 35(97.2%) | 23(82.1%) | 58(90.6%) | 0.040 |
Without | 1 (2.8%) | 5(17.8%) | 6(9.4%) | 0.040 |
The compression of structures | ||||
With | 4 (11.1%) | 3(10.7%) | 7(10.9%) | <0.001 |
Without | 32(88.9%) | 25(89.2%) | 57(89.1%) | - |
Age at discovery of tumor lesion (m) | ||||
Mean (range) | 1.92 (range1–5) | 30.2 (range 6–144 ) | 14.3 (range 1–144 ) | - |
Imaging characteristics | ||||
Location | ||||
Head–neck area | 7(19.4%) | 2(7.1%) | 9(14.1%) | 0.160 |
Extremities | 16(44.4%) | 18(64.3%) | 34(53.1%) | 0.115 |
Trunk | 5(13.9%) | 5(17.9%) | 10(15.6%) | 0.664 |
Multiple anatomical regions | 8(22.2%) | 3(10.7%) | 11(17.2%) | 0.226 |
Morphological type | ||||
Solitary lesion | 14(38.9%) | 18(64.3%) | 32(50.0%) | 0.044 |
Infiltrative lesion | 22(61.1%) | 10(35.7%) | 32(50.0%) | 0.044 |
Destructive changes or remodeling of adjacent bone | 9 (25.0%) | 18(64.3%) | 27(42.2%) | 0.002 |
Destruction of the adjacent cortex | 8 (22.2%) | 18(64.3%) | 26(40.6%) | 0.001 |
Injury of the epiphyseal region | 1(2.8%) | 5(17.9%) | 6(9.4%) | 0.040 |
Invasion to near joints | 4(11.1%) | 10 (35.7%) | 14(21.9%) | 0.018 |
Maximal tumor dimension (cm) | 7.70 (1.91–15.20 ) | 5.53 (0.86–9.77 ) | 6.77 (0.86-15.20) | - |
Vascularity | 6 (16.7%) | 3 (10.7%) | 9 (14.1%) | 0.497 |
Edema or swelling | 12 (33.3%) | 16 (57.1%) | 28 (43.8%) | 0.057 |