Fig. 4

Prognostic Factors of Children with Critical COVID-19. a PCA was used to identify correlated variables for distinguishing critical cases (group B) from common and severe cases (group A) on admission. The 10 most contributory variables, i.e., CD3⁺ T cells (T), red blood cells, CD3⁺CD8⁺ T cells (Tc), interleukin-10 (IL-10), hemoglobin, CD3⁺CD4⁺ T cells (Th), IL-6, lymphocytes, CD19+ B cells (B), and interferon-γ (IFN-γ) were identified. b The ROC curve and AUC were calculated for the 10 parameters using the R package pROC. T, Th, Tc, IL-6, IL-10, red blood cells, and hemoglobin had AUC values of > 0.85