Table 4 Crude and adjusted Cox-proportional hazard regression output for the predictors of opportunistic infections among HIV -infected paediatrics at JMC, April 10–May 10, 2017
Variables | OIs | CHR [95%CI] | p-value | AHR[95%CI] | p-value | ||
|---|---|---|---|---|---|---|---|
Yes | No | ||||||
Sex | Male | 30 (30.6 | 68 (69.4) | 1 | |||
Female | 28 (34.6) | 53 (65.4) | 0.94 [0.55–1.59] | 0.810 | |||
Age: Median IQR | 7 (4–9) | 58 (32.4) | 121 (67.6) | 1.00 [0.91–1.09] | 0.995 | ||
Base-line body mass index | Below 5th centile | 53 (37.9) | 87 (62.1) | 3.63 [1.45–9.10] | 0.006 | ||
Above 5thcentile | 5 (12.8) | 34 (87.2) | 1 | ||||
Weight for height | < 70% | 15 (41.7) | 21 (58.3) | 1.34 [0.74–2.44] | 0.332 | ||
70–85% | 2 (14.3) | 12 (85.7) | 0.42 [0.10–1.73] | 0.229 | |||
> 85% | 41 (31.8) | 88 (68.2) | 1 | ||||
In care of the child | Mother | 7 (29.2) | 17 (70.8) | 1 | |||
Other | 51 (32.9) | 104 (67.1) | 0.66 [0.28–1.54] | 0.332 | |||
Maternal status | Live | 47 (32.2) | 99 (67.8) | 1 | |||
Dead | 11 (33.3) | 22 (66.7) | 1.17 [0.59–2.32] | 0.654 | |||
Maternal sero-status | Unknown | 6 (33.3) | 12 (66.7) | 0.71 [0.28–1.81] | 0.476 | ||
Negative | 52 (32.3) | 109 (67.7) | 1 | ||||
Paternal status | Live | 43 (32.6) | 89 (67.4) | 1 | |||
Dead | 15 (31.9) | 32 (68.1) | 0.88 [0.48–1.62] | 0.694 | |||
Residence | Urban | 49 (36.6) | 85 (63.4) | 1 | |||
Rural | 9 (20) | 36 (80) | 1.81 [0.885–3.69] | 0.104 | |||
ART group | ABC | 27 (31) | 60 (69) | 1.05 [0.62–1.76] | 0.885 | ||
AZT | 29 (31.5) | 63 (68.5) | 1 | ||||
CD4 counta | 162 (117–221) | 58 (32.4) | 121 (67.6) | 0.98 [0.97–0.98] | < 0.001 | 0.99 [0.98–0.99] | < 0.001 |
Baseline Viral load | < 1000copes/ml | 36 (24.7) | 110 (75.3) | 1 | 1 | ||
>1000copes/ml | 19 (65.5) | 10 (34.5) | 2.87 [1.62–5.10] | < 0.001 | 1.72 [0.91–3.24] | 0.094 | |
WHO Stage | Stage I | 5 (45.5) | 6 (54.5) | 1 | |||
Stage II | 15 (23.4) | 49 (76.6) | 0.39 [0.14–1.06] | 0.066 | |||
Stage III | 31 (35.6) | 56 (64.4) | 0.59 [0.23–1.52] | 0.276 | |||
Stage IV | 7 (41.2) | 10 (58.8) | 0.80 [0.25–2.53] | 0.707 | |||
Baseline nutritional status | Normal | 4 (3.9) | 98 (96.1) | 1 | 1 | ||
SAM | 54 (70.1) | 23 (29.9) | 28.37 [10.23–78.73] | < 0.001 | 15.92 [5.34–47.50] | < 0.001 | |
TB treatment | No | 46 (27.7) | 120 (72.3) | 1 | 1 | ||
Yes | 12 (92.3) | 1 (7.7) | 8.58 [4.33–17.01] | < 0.001 | 2.93 [1.39–6.17] | 0.005 | |