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Table 1 Comparative baseline characteristics of the cohort at JMC, April 10–May 10, 2017

From: Abacavir versus Zidovudine-based regimens for treatment of HIV-infected children in resource limited settings: a retrospective cohort study

All n = 179

ABC group (n = 87)

AZT group (n = 92)

P-value

Variables

Sex

Male

42 (48.3%)

39 (42.4%)

0.42

Female

45 (51.7%)

53 (57.6%)

Age (years)

< 3 years

11 (12.6%)

12 (13.0%)

0.97

3–5 years

18 (20.7%)

20 (21.7%)

>  5 years

58 (66.7%)

60 (65.2%)

BMI (baseline)

<5th centile

74 (85.0%)

66 (71.7%)

0.03

>5th centile

13 (14.9%)

26 (28.3%)

Maternal HIV status

Positive

78 (89.7%)

83 (90.2%)

0.91

Unknown

9 (10.3%)

9 (9.8%)

Area of residence

Urban

66 (75.9%)

68 (73.9%)

0.76

Rural

21 (24.1%)

24 (26.1%)

Baseline CD4+ (Mean + SD)

166.31 + 76.22

178.78 + 71.12

0.26

WHO stage

I

8 (9.2%)

3 (3.3%)

0.08

II

24 (27.6%)

40 (43.5%)

III

45 (51.7%)

42 (45.7%)

IV

10 (11.5%)

7 (7.6%)

Functional status

W/A

72 (82.8%)

88 (95.7%)

0.001

A/D

12 (13.8%)

0 (0.0%)

B/R

3 (3.4%)

4 (4.3%)

TB (treatment)

Yes

3 (3.4%)

9 (9.8%)

0.06

No

84 (96.6%)

83 (90.2%)

OI Prophylaxis

Both CPT and INH

85 (97.7%)

89 (96.7%)

0.69

CPT only

1 (1.1%)

1 (1.1%)

Neither

1 (1.1%)

2 (2.2%)

Nutritional status

Normal

45 (51.7%)

57 (62.0%)

0.17

SAM

42 (48.3%)

35 (38.0%)

  1. BMI body mass index, W/A working/Appropriate, A/D Ambulatory/Delay, B/R Bedridden/regression, TB Tuberculosis, CPT cotrimoxazole preventative therapy, INH Isoniazid, CD4 cluster of differentiation, SD Standard deviation, OIs opportunistic infections