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Table 3 Factors of gastrointestinal perforation in 6-month tracking stratified by variables listed in the table by using Cox regression

From: The incidence of collagen-associated adverse events in pediatric population with the use of fluoroquinolones: a nationwide cohort study in Taiwan

FluoroquinolonesWithWithoutRatioWith vs. Without
StratifiedEventsPDsRate (per 105 PDs)EventsPDsRate (per 105 PDs)Adjusted HR95% CI95% CIP
Total175,940,776.060.296823,707,602.750.290.9981.3300.7782.2760.255
Gender
 Male103,060,435.000.333112,297,000.620.251.2961.7440.9212.9830.643
 Female72,880,341.060.243711,410,602.120.320.7491.0080.5561.7240.297
Age group (years)
 < 11183,600.000.544820,422.120.491.1171.5030.8762.5720.675
 12256,265.940.783876,927.190.342.2812.2790.9984.0270.052
 21286,506.190.3541,024,530.500.390.8941.1940.7021.9600.536
 32325,930.750.6151,282,879.440.391.5741.8220.9432.8940.071
 41384,465.190.2661,542,322.120.390.6690.8990.5251.2750.489
 5–931,677,499.810.18146,622,008.940.210.8461.1390.6691.9490.376
 10–1421,521,852.940.13106,123,547.690.160.8051.0800.6351.8510.447
1551,304,655.250.38225,414,964.750.410.9431.2710.7422.1700.285
Catastrophic illness
 Without165,907,063.870.276823,616,531.120.290.9411.2640.7352.1630.194
 With133,712.192.97091,071.620.000.796
Low-income household
 Without165,789,090.440.286823,320,517.250.290.9481.2770.7442.1830.182
 With1151,685.620.660387,085.500.000.785
Season
 Spring51,209,564.810.41236,731,139.190.341.2101.6280.9522.7920.073
 Summer31,211,624.370.25125,549,493.380.221.1451.5390.9012.6390.102
 Autumn21,596,290.690.13105,377,612.870.190.6740.9070.5241.5510.773
 Winter71,923,296.190.36236,049,357.310.380.9571.2880.7512.2040.288
Urbanization level
 1 (the highest)61,305,977.190.46306,700,633.870.451.0261.3780.8082.3640.134
 222,119,226.310.09128,911,079.560.130.7010.9420.5531.6160.446
 371,142,905.310.61193,835,392.810.501.2361.6630.9712.8430.059
 4 (the lowest)21,372,667.250.1574,260,496.500.160.8871.1850.6922.0410.334
Level of care
 Hospital center6222,455.872.70261,083,958.872.401.1241.1560.8842.5880.240
 Regional hospital5343,936.381.45191,737,590.941.091.3291.7940.9723.0590.062
 Local hospital4281,046.941.42151,249,182.121.201.1851.5890.9322.7350.179
 Physician clinics25,093,336.870.04819,636,870.810.040.9641.2900.7592.2140.304
  1. PDs Person-days, Adjusted HR Adjusted Hazard ratio: Adjusted for the variables listed in Table 2, CI Confidence interval