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Table 8 Correlations between the five core metabolites and the other 71 analyzed metabolites

From: Altered metabolism of mothers of young children with Autism Spectrum Disorder: a case control study

Metabolite Correlation Coefficient p-Value
Glu-Cys
 tGSH 0.55 5.71E-06
 tGSH/GSSG 0.35 0.01
 6-hydroxyindole sulfate −0.25 0.05
 SAM/SAH −0.26 0.04
 N-formylanthranilic acid −0.28 0.03
 5-methylthioadenosine (MTA) −0.28 0.03
 Pyridoxate −0.31 0.02
 Folate −0.38 3.40E-03
Histidylglutamate
 Asparaginylalanine 0.55 6.74E-06
 Mannose 0.40 1.70E-03
 fCystine 0.30 0.02
 Succinylcarntine (C4-DC) −0.27 0.04
 Citrulline −0.27 0.04
 Fructose −0.28 0.03
 Octanoylcarnitine (C8) −0.29 0.02
 Gamma-glutamylglycine −0.30 0.02
 Isovaleryglycine −0.32 0.01
 Decanoylcarnitine (C10) −0.33 0.01
Cinnamoylglycine
 N-acetyl-2-aminooctanoatea 0.45 4.13E-04
 N-formylanthranilic acid 0.44 4.30E-04
 3-indoxyl sulfate 0.35 0.01
 Citrulline 0.33 0.01
 6-hydroxyindole sulfate 0.32 0.01
 Chlorotyrosine 0.29 0.02
 Alpha-ketoglutaramatea 0.28 0.03
 Nicotinamide adenine dinucleotide (NAD+) 0.28 0.03
 Pyridoxate 0.27 0.04
 Guaiacol sulfate 0.26 0.04
 S-methylglutathione 0.26 0.04
 Methionine −0.29 0.02
 fCysteine −0.33 0.01
Proline
 S-1-pyrroline-5-carboxylate 0.59 1.22E-06
 Gamma-glutamyltyrosine 0.45 3.73E-04
 3-indoxyl sulfate 0.44 5.33E-04
 6-hydroxyindole sulfate 0.43 6.01E-04
 Phenol sulfate 0.41 1.20E-03
 Glutamine 0.36 0.01
 Propionylglycine 0.35 0.01
 Glycine 0.35 0.01
 Gamma-glutamylglycine 0.32 0.01
 5-oxoproline 0.30 0.02
 Alpha-ketoglutaramatea 0.28 0.03
 Folate 0.28 0.03
 N-formylanthranilic acid 0.27 0.04
 Adenosine −0.30 0.02
Adrenoylcarnitine (C22:4)a
 Arachidonoylcarnitine (C20:4) 0.93 8.00E-26
 Docosapentaenoylcarnitine (C22:5n3)a 0.85 8.64E-18
 Eicosenoylcarnitine (C20:1)a 0.74 2.35E-11
 Palmitoylcarnitine (C16) 0.70 8.13E-10
 Myristoylcarnitine (C14) 0.69 2.17E-09
 Laurylcarnitine (C12) 0.49 8.88E-05
 Fructose 0.41 1.20E-03
 N-acetylasparagine 0.38 2.60E-03
 Stearoylcarnitine (C18) 0.31 0.02
 Methionine 0.26 0.04
 Cys-Gly 0.26 0.05
 Arachidoylcarnitine (C20)a 0.26 0.05
 N-palmitoylserine 0.25 0.05
 fCysteine/fCystine −0.29 0.03
 fCystine −0.30 0.02
  1. The a indicates metabolites measured by Metabolon that have not been officially confirmed by a standard, but Metabolon is confident in the metabolite’s identity