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Table 8 Correlations between the five core metabolites and the other 71 analyzed metabolites

From: Altered metabolism of mothers of young children with Autism Spectrum Disorder: a case control study

Metabolite

Correlation Coefficient

p-Value

Glu-Cys

 tGSH

0.55

5.71E-06

 tGSH/GSSG

0.35

0.01

 6-hydroxyindole sulfate

−0.25

0.05

 SAM/SAH

−0.26

0.04

 N-formylanthranilic acid

−0.28

0.03

 5-methylthioadenosine (MTA)

−0.28

0.03

 Pyridoxate

−0.31

0.02

 Folate

−0.38

3.40E-03

Histidylglutamate

 Asparaginylalanine

0.55

6.74E-06

 Mannose

0.40

1.70E-03

 fCystine

0.30

0.02

 Succinylcarntine (C4-DC)

−0.27

0.04

 Citrulline

−0.27

0.04

 Fructose

−0.28

0.03

 Octanoylcarnitine (C8)

−0.29

0.02

 Gamma-glutamylglycine

−0.30

0.02

 Isovaleryglycine

−0.32

0.01

 Decanoylcarnitine (C10)

−0.33

0.01

Cinnamoylglycine

 N-acetyl-2-aminooctanoatea

0.45

4.13E-04

 N-formylanthranilic acid

0.44

4.30E-04

 3-indoxyl sulfate

0.35

0.01

 Citrulline

0.33

0.01

 6-hydroxyindole sulfate

0.32

0.01

 Chlorotyrosine

0.29

0.02

 Alpha-ketoglutaramatea

0.28

0.03

 Nicotinamide adenine dinucleotide (NAD+)

0.28

0.03

 Pyridoxate

0.27

0.04

 Guaiacol sulfate

0.26

0.04

 S-methylglutathione

0.26

0.04

 Methionine

−0.29

0.02

 fCysteine

−0.33

0.01

Proline

 S-1-pyrroline-5-carboxylate

0.59

1.22E-06

 Gamma-glutamyltyrosine

0.45

3.73E-04

 3-indoxyl sulfate

0.44

5.33E-04

 6-hydroxyindole sulfate

0.43

6.01E-04

 Phenol sulfate

0.41

1.20E-03

 Glutamine

0.36

0.01

 Propionylglycine

0.35

0.01

 Glycine

0.35

0.01

 Gamma-glutamylglycine

0.32

0.01

 5-oxoproline

0.30

0.02

 Alpha-ketoglutaramatea

0.28

0.03

 Folate

0.28

0.03

 N-formylanthranilic acid

0.27

0.04

 Adenosine

−0.30

0.02

Adrenoylcarnitine (C22:4)a

 Arachidonoylcarnitine (C20:4)

0.93

8.00E-26

 Docosapentaenoylcarnitine (C22:5n3)a

0.85

8.64E-18

 Eicosenoylcarnitine (C20:1)a

0.74

2.35E-11

 Palmitoylcarnitine (C16)

0.70

8.13E-10

 Myristoylcarnitine (C14)

0.69

2.17E-09

 Laurylcarnitine (C12)

0.49

8.88E-05

 Fructose

0.41

1.20E-03

 N-acetylasparagine

0.38

2.60E-03

 Stearoylcarnitine (C18)

0.31

0.02

 Methionine

0.26

0.04

 Cys-Gly

0.26

0.05

 Arachidoylcarnitine (C20)a

0.26

0.05

 N-palmitoylserine

0.25

0.05

 fCysteine/fCystine

−0.29

0.03

 fCystine

−0.30

0.02

  1. The a indicates metabolites measured by Metabolon that have not been officially confirmed by a standard, but Metabolon is confident in the metabolite’s identity