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Table 2 Description of reactions

From: The use of direct oral challenge to confirm allergies to penicillin class antibiotics in Danish children

 

Total

Negative

Positive

Reaction to AB before referral to DC

140

136

4

 Once

128 (91%)

124 (91%)

4 (100%)

 More than once

12 (8.6%)

12 (8.8%)

 

Time period from AB dose to symptoms

135

131

4

  < 1 day

86 (64%)

84 (64%)

2 (50%)

 1–2 days

27 (20%)

25 (19%)

2 (50%)

  > 2 days

22 (16%)

22 (17%)

 

Duration of symptoms

137

133

4

  < 1 day

66 (48%)

63 (47%)

3 (75%)

  > 1 day

60 (44%)

59 (44%)

1 (25%)

 Unknown

11 (8.0%)

11 (8.3%)

 

Medical treatment

136

132

4

 None

105 (77%)

103 (78%)

2 (50%)

 Antihistamines

30 (22%)

28 (21%)

2 (50%)

 Corticosteroids

8 (5.8%)

8 (6.1%)

 

 Epinephrine

1 (0.7%)

1 (0.8%)

 

 Bronchodilators

2 (1.5%)

2 (1.5%)

 

Indication of AB treatment

133

129

4

 Airway infection

17 (13%)

16 (12%)

1 (25%)

 Tonsillitis

21 (16%)

21 (16%)

 

 Sinusitis/otitis

76 (57%)

73 (57%)

3 (75%)

 Other (impetigo, arthritis etc.)

15 (11%)

15 (12%)

 

 Unknown

4 (3.0%)

4 (3.1%)

 
  1. Total: all children; Negative: children with a negative provocation test; Positive: children with a positive provocation test