Table 2 Univariate analysis of the factors associated with quantitative data in HSPN patients with and without crescent formation
Variables | Grade I-II n = 146 | Grade III-V n = 45 | P |
|---|---|---|---|
C-reactive protein, mg/l | 3.6629 ± 8.0603 | 6.5598 ± 11.712 | 0.0307* |
White blood cell count, × 109/l | 10.029 ± 4.0135 | 11.723 ± 3.8933 | 0.0135 |
Lymphocyte, % | 28.412 ± 12.924 | 24.107 ± 13.352 | 0.0540 |
Platelet count, ×109/l | 309.17 ± 88.675 | 343.07 ± 82.524 | 0.0239 |
Complement component 3, g/l | 1.1476 ± 0.1881 | 1.2171 ± 0.1938 | 0.0330 |
Complement component 4, g/l | 0.2555 ± 0.0857 | 0.2822 ± 0.0875 | 0.0707 |
Immunoglobulin A, g/l | 2.2246 ± 0.8366 | 2.3653 ± 0.8168 | 0.3237 |
Immunoglobulin G, g/l | 9.601 ± 2.495 | 9.1013 ± 2.3659 | 0.2371 |
Immunoglobulin M, g/l | 1.181 ± 0.5038 | 1.2353 ± 0.5734 | 0.5425 |
Total cholesterol, mmol/l | 4.2461 ± 1.2149 | 5.1396 ± 1.5511 | <0.0001 |
Triglyceride, mmol/l | 1.2288 ± 0.7094 | 1.6627 ± 0.9239 | 0.0006* |
Serum uric acid, mmol/l | 267.91 ± 83.918 | 266.55 ± 78.065 | 0.9232 |
Blood urea nitrogen, mmol/l | 4.4997 ± 1.2614 | 4.6858 ± 1.4228 | 0.4031 |
Serum creatinine, mmol/l | 39.261 ± 10.863 | 38.998 ± 8.1706 | 0.7791* |
CD4+/CD8+, % | 1.1854 ± 0.3808 | 1.1422 ± 0.4351 | 0.5220 |
CD3+, % | 67.1528 ± 10.3439 | 66.1283 ± 9.3301 | 0.5504 |
CD3 + CD4+, % | 32.488 ± 7.649 | 31.087 ± 8.6809 | 0.3005 |
CD3 + CD8+, % | 28.1910 ± 6.1454 | 28.9500 ± 6.2194 | 0.4680 |
CD19 + CD23+, % | 9.0250 ± 3.8344 | 8.6178 ± 3.6392 | 0.5300 |
Mycoplasma IgG, AU/l | 68.3077 ± 65.7568 | 71.9142 ± 73.0422 | 0.7652 |
Mycoplasma IgM, COL | 1.0552 ± 0.8047 | 1.0084 ± 0.6630 | 0.7329 |
Anti-streptolysin O, IU/ml | 161.0 ± 264.4 | 150.0 ± 141.8 | 0.1712* |
24 h urinary microalbumin, mg | 269.2 ± 293.6 | 565.7 ± 330.4 | <0.0001 |
24 h urinary total protein, mg | 542.32 ± 821.84 | 1799.5 ± 1778.9 | <0.0001 |
Urinary RBC count, /UL | 94.49 ± 233.54 | 630.65 ± 1505.9 | <0.0001* |
Urinary WBC count, /UL | 20.255 ± 63.389 | 80.811 ± 132.25 | <0.0001* |
N-acetylglucosaminidase, U/L | 26.003 ± 16.885 | 34.677 ± 33.282 | 0.0310* |
α1-Microglobulin, U/L | 7.359 ± 4.9073 | 9.333 ± 5.0892 | 0.0204 |
β2-Microglobulin, U/L | 0.3357 ± 0.4068 | 0.3231 ± 0.1824 | 0.5001* |
Urinary transferrin, mg/l | 24.014 ± 34.348 | 75.179 ± 42.057 | <0.0001* |
Urinary microalbumin/creatinine, mg/mg | 0.2835 ± 0.2725 | 0.7933 ± 0.5126 | <0.0001* |
Prothrombin time, s | 12.698 ± 1.2648 | 12.293 ± 1.3303 | 0.0659 |
D-dimer, μg/l | 928.71 ± 1645.2 | 1177.3 ± 1941.1 | 0.4177 |
Fibrinogen, g/l | 2.5638 ± 0.7827 | 2.7704 ± 0.9135 | 0.1394 |
Antithrombin III, % | 110.97 ± 17.292 | 109.79 ± 22.1 | 0.7695* |
Thrombin time, s | 17.732 ± 1.72 | 17.704 ± 1.9175 | 0.9275 |
Activated partial thrombin time, s | 32.706 ± 7.7257 | 30.46 ± 8.4283 | 0.0975 |
Weight, kg | 32.762 ± 12.69 | 34.611 ± 14.598 | 0.4110 |