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Table 2 Proportion and odds ratio of receipt of at least one dose of palivizumab

From: RSV prophylaxis use in high-risk infants in Western Australia, 2002-2013: a record linkage cohort study

Characteristic

Infants receiving at least 1 dose of palivizumab N = 271

Infants receiving no palivizumab N = 24,058

Univariable

Multivariable

n

(%)

n

(%)

OR

(95% CI)

aOR

(95% CI)

Sex

 Males

157

(57.9)

13,280

(55.2)

Ref

 

Ref

 

 Females

114

(42.1)

10,776

(44.8)

0.9

(0.7–1.1)

Year of birth

 2002–2009

52

(19.2)

14,844

(61.7)

Ref

 

Ref

 

 2010–2013

219

(80.8)

9214

(38.3)

6.8

(5.0–9.2)

8.8

(6.1–12.6)

Indigenous status

 Non-Aboriginal

238

(87.8)

21,086

(87.6)

Ref

 

Ref

 

 Aboriginal

33

(12.2)

2972

(12.4)

1.0

(0.7–1.4)

0.8

(0.4–1.4)

Gestational age

  < 28 weeks

208

(76.8)

1007

(4.2)

66.4

(46.2–95.6)

7.4

(1.8–30.9)

 28–32 weeks

15

(5.5)

3688

(15.3)

1.3

(0.7–2.4)

0.5

(0.1–1.9)

 33–36 weeks

13

(4.8)

8107

(33.7)

0.5

(0.3–1.0)

0.5

(0.2–1.2)

  ≥ 37 weeks

35

(12.9)

11,256

(46.8)

Ref

 

Ref

 

Birth weight

  < 1500 g

221

(81.5)

2926

(12.2)

22.3

(13.0–38.3)

1.5

(0.4–6.3)

 1500–2499 g

14

(5.2)

7786

(32.4)

0.5

(0.3–1.1)

0.9

(0.4–2.1)

 2500–2999 g

14

(5.2)

4132

(17.2)

Ref

 

Ref

 

 3000–3499 g

13

(4.8)

4341

(18.0)

0.9

(0.4–1.9)

0.6

(0.3–1.4)

  ≥ 3500 g

9

(3.3)

4873

(20.3)

0.6

(0.2–1.3)

0.4

(0.2–1.0)

Geographical area of birth

 Metropolitan

196

(72.3)

19,010

(79.0)

Ref

 

Ref

 

 Rural

55

(20.3)

3262

(13.6)

1.6

(1.2–2.2)

1.6

(1.0–2.5)

 Remote

19

(7.0)

1701

(7.1)

1.1

(0.7–1.7)

0.9

(0.4–1.9)

Major congenital anomalies

 No

145

(53.5)

22,061

(91.7)

Ref

 

Ref

 

 Yes

126

(46.5)

1997

(8.3)

9.6

(7.5–12.2)

3.8

(2.7–5.4)

Congenital heart disease

 No

45

(16.6)

21,709

(90.2)

Ref

 

Ref

 

 Yes

226

(83.4)

2259

(9.4)

48.3

(35.0–66.7)

5.8

(3.8–8.9)

Chronic lung disease

 No

79

(29.2)

23,111

(96.1)

Ref

 

Ref

 

 Yes

192

(70.8)

947

(3.9)

59.3

(45.3–77.7)

2.8

(1.8–4.5)

Season of birth

 Spring

38

(14.0)

5918

(24.6)

Ref

 

Ref

 

 Summer

43

(15.9)

6005

(25.0)

1.1

(0.7–1.7)

1.1

(0.6–1.9)

 Autumn

104

(38.4)

6170

(25.6)

2.6

(1.8–3.8)

4.2

(2.6–6.7)

 Winter

86

(31.7)

5965

(24.8)

2.3

(1.5–3.3)

3.4

(2.1–5.6)

Multiple birth

 Singleton

221

(81.5)

20,527

(85.3)

Ref

 

Ref

 

 Multiple

50

(18.5)

3495

(14.5)

1.3

(1.0–1.8)

0.6

(0.4–0.9)

Number of previous pregnancies

 0

90

(33.2)

7595

(31.6)

Ref

 

Ref

 

 1

70

(25.8)

6272

(26.1)

0.9

(0.7–1.3)

1.3

(0.9–1.9)

 2

33

(12.2)

4044

(16.8)

0.7

(0.5–1.0)

1.1

(0.7–1.9)

  ≥ 3

78

(28.8)

6111

(25.4)

1.1

(0.8–1.5)

1.4

(0.9–2.1)

Socioeconomic status

 0–10% (most dis)

42

(15.5)

2967

(12.3)

Ref

 

Ref

 

 10–25%

38

(14.0)

4628

(19.2)

0.6

(0.4–0.9)

0.6

(0.4–1.1)

 25–75%

134

(49.4)

10,688

(44.4)

0.9

(0.6–1.3)

0.8

(0.5–1.2)

 75–90%

28

(10.3)

2780

(11.6)

0.7

(0.4–1.2)

0.8

(0.5–1.6)

 90–100%

12

(4.4)

1213

(5.0)

0.7

(0.4–1.3)

0.7

(0.3–1.5)

Mother smoking during pregnancy

 No

224

(82.7)

18,861

(78.4)

Ref

 

Ref

 

 Yes

47

(17.3)

5161

(21.5)

0.8

(0.6–1.1)

1.0

(0.6–1.5)