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Table 2 Proportion and odds ratio of receipt of at least one dose of palivizumab

From: RSV prophylaxis use in high-risk infants in Western Australia, 2002-2013: a record linkage cohort study

Characteristic Infants receiving at least 1 dose of palivizumab N = 271 Infants receiving no palivizumab N = 24,058 Univariable Multivariable
n (%) n (%) OR (95% CI) aOR (95% CI)
Sex
 Males 157 (57.9) 13,280 (55.2) Ref   Ref  
 Females 114 (42.1) 10,776 (44.8) 0.9 (0.7–1.1)
Year of birth
 2002–2009 52 (19.2) 14,844 (61.7) Ref   Ref  
 2010–2013 219 (80.8) 9214 (38.3) 6.8 (5.0–9.2) 8.8 (6.1–12.6)
Indigenous status
 Non-Aboriginal 238 (87.8) 21,086 (87.6) Ref   Ref  
 Aboriginal 33 (12.2) 2972 (12.4) 1.0 (0.7–1.4) 0.8 (0.4–1.4)
Gestational age
  < 28 weeks 208 (76.8) 1007 (4.2) 66.4 (46.2–95.6) 7.4 (1.8–30.9)
 28–32 weeks 15 (5.5) 3688 (15.3) 1.3 (0.7–2.4) 0.5 (0.1–1.9)
 33–36 weeks 13 (4.8) 8107 (33.7) 0.5 (0.3–1.0) 0.5 (0.2–1.2)
  ≥ 37 weeks 35 (12.9) 11,256 (46.8) Ref   Ref  
Birth weight
  < 1500 g 221 (81.5) 2926 (12.2) 22.3 (13.0–38.3) 1.5 (0.4–6.3)
 1500–2499 g 14 (5.2) 7786 (32.4) 0.5 (0.3–1.1) 0.9 (0.4–2.1)
 2500–2999 g 14 (5.2) 4132 (17.2) Ref   Ref  
 3000–3499 g 13 (4.8) 4341 (18.0) 0.9 (0.4–1.9) 0.6 (0.3–1.4)
  ≥ 3500 g 9 (3.3) 4873 (20.3) 0.6 (0.2–1.3) 0.4 (0.2–1.0)
Geographical area of birth
 Metropolitan 196 (72.3) 19,010 (79.0) Ref   Ref  
 Rural 55 (20.3) 3262 (13.6) 1.6 (1.2–2.2) 1.6 (1.0–2.5)
 Remote 19 (7.0) 1701 (7.1) 1.1 (0.7–1.7) 0.9 (0.4–1.9)
Major congenital anomalies
 No 145 (53.5) 22,061 (91.7) Ref   Ref  
 Yes 126 (46.5) 1997 (8.3) 9.6 (7.5–12.2) 3.8 (2.7–5.4)
Congenital heart disease
 No 45 (16.6) 21,709 (90.2) Ref   Ref  
 Yes 226 (83.4) 2259 (9.4) 48.3 (35.0–66.7) 5.8 (3.8–8.9)
Chronic lung disease
 No 79 (29.2) 23,111 (96.1) Ref   Ref  
 Yes 192 (70.8) 947 (3.9) 59.3 (45.3–77.7) 2.8 (1.8–4.5)
Season of birth
 Spring 38 (14.0) 5918 (24.6) Ref   Ref  
 Summer 43 (15.9) 6005 (25.0) 1.1 (0.7–1.7) 1.1 (0.6–1.9)
 Autumn 104 (38.4) 6170 (25.6) 2.6 (1.8–3.8) 4.2 (2.6–6.7)
 Winter 86 (31.7) 5965 (24.8) 2.3 (1.5–3.3) 3.4 (2.1–5.6)
Multiple birth
 Singleton 221 (81.5) 20,527 (85.3) Ref   Ref  
 Multiple 50 (18.5) 3495 (14.5) 1.3 (1.0–1.8) 0.6 (0.4–0.9)
Number of previous pregnancies
 0 90 (33.2) 7595 (31.6) Ref   Ref  
 1 70 (25.8) 6272 (26.1) 0.9 (0.7–1.3) 1.3 (0.9–1.9)
 2 33 (12.2) 4044 (16.8) 0.7 (0.5–1.0) 1.1 (0.7–1.9)
  ≥ 3 78 (28.8) 6111 (25.4) 1.1 (0.8–1.5) 1.4 (0.9–2.1)
Socioeconomic status
 0–10% (most dis) 42 (15.5) 2967 (12.3) Ref   Ref  
 10–25% 38 (14.0) 4628 (19.2) 0.6 (0.4–0.9) 0.6 (0.4–1.1)
 25–75% 134 (49.4) 10,688 (44.4) 0.9 (0.6–1.3) 0.8 (0.5–1.2)
 75–90% 28 (10.3) 2780 (11.6) 0.7 (0.4–1.2) 0.8 (0.5–1.6)
 90–100% 12 (4.4) 1213 (5.0) 0.7 (0.4–1.3) 0.7 (0.3–1.5)
Mother smoking during pregnancy
 No 224 (82.7) 18,861 (78.4) Ref   Ref  
 Yes 47 (17.3) 5161 (21.5) 0.8 (0.6–1.1) 1.0 (0.6–1.5)