Table 3 Genotypic and allelic distribution of APLN T-1860C and APLNR G212A polymorphisms in non-obese and obese children
From: Relationships of apelin concentration and APLN T-1860C polymorphism with obesity in Thai children
APLN T-1860C | Obese n (%) | Non-obese n (%) | Genotypic or allelic P-value |
Total: genotype | |||
 CC | 52 (26.3) | 25 (19.7) |  |
 CT | 41 (20.7) | 25 (19.7) | 0.325 |
 TT | 105 (53.0) | 77 (60.6) |  |
 TT vs CT + CCa | 1.36 (0.87–2.15) |  |  |
[0.170] | Â | Â | |
 C allele | 145 (0.366) | 75 (0.295) | 0.062 |
 T allele | 251 (0.634) | 179 (0.705) |  |
Female: genotype | |||
 CC | 17 (18.7) | 5 (7.7) |  |
 CT | 41 (45.0) | 25 (38.5) | 0.042* |
 TT | 33 (36.3) | 35 (53.8) |  |
 TT vs CT + CCa | 2.05 (1.08–3.92) [0.029]* | Reference |  |
 C allele | 75 (0.412) | 35 (0.269) | 0.009** |
 T allele | 107 (0.588) | 95 (0.731) |  |
Male: genotype | |||
 CC | -b | -b |  |
 CT | - b | - b |  |
 TT | - b | - b |  |
 T vs Ca | 1.02 (0.52–2.00) [0.902] | Reference |  |
 C allele | 70 (0.327) | 40 (0.323) | 0.931 |
 T allele | 144 (0.673) | 84 (0.677) |  |
APLNR G212A | Obese n (%) | Non-obese n (%) | Genotypic or allelic P-value |
Total: genotype | |||
 AA | 3 (1.5) | 4 (3.2) | 0.121 |
 AG | 52 (26.3) | 22 (17.3) |  |
 GG | 143 (72.2) | 101 (79.5) |  |
 GG vs AA+AGa | 1.49 (0.88–2.54) | Reference |  |
[0.137] | Â | ||
 A allele | 58 (0.146) | 30 (0.118) | 0.303 |
 G allele | 338 (0.854) | 224 (0.882) |  |
Female: genotype | |||
 AA | 1 (1.1) | 2 (3.1) | 0.297 |
 AG | 22 (24.2) | 10 (15.4) |  |
 GG | 68 (74.7) | 53 (81.5) |  |
 GG vs AA+AGa | 1.49 (0.68–3.28) [0.310] | Reference |  |
 A allele | 24 (0.132) | 14 (0.108) | 0.432 |
 G allele | 158 (0.868) | 116 (0.892) |  |
Male: genotype | |||
 AA | 2 (1.9) | 2 (3.2) |  |
 AG | 30 (28.0) | 12 (19.4) | 0.410 |
 GG | 75 (70.1) | 48 (77.4) |  |
 GG vs AA+AGa | 1.43 (0.70–2.96) [0.330] | Reference |  |
 A allele | 34 (0.159) | 16 (0.129) | 0.456 |
 G allele | 180 (0.841) | 108 (0.871) |  |