Epidemiology, prenatal diagnosis, and neonatal outcomes of congenital heart defects in eastern China: a hospital-based multicenter study

Table 1 Patients’ characteristics and risk factors for CHD

Variable	Births (n)	CHD (n)	Incidence (per 1000 births)	OR value and 95% CI	P value
Maternal age (years)
< 20	9879	312	31.8	2.11(1.88–2.31)	< 0.001
21–34	456,027	6944	15.3	Ref
≥35	68,096	1290	18.9	1.25(1.18–1.33)	< 0.001
Area
Urban	320,029	6343	19.8	1.24(1.18–1.31)	< 0.001
Rural	138,754	2203	15.9	Ref
Birth gender
Male	253,015	4614	18.2	1.34(1.28–1.40)	< 0.001
Female	280,921	3843	13.7	Ref
Unknown	–	65	–	–	–
Singleton	524,108	7965	15.2	Ref
Multiple birth	9894	581	58.7	4.03(3.70–4.40)	< 0.001

ISSN: 1471-2431