BMC Pediatrics

Table 3 Associations between HPA axis rhythm index and anthropometry

From: Evidence for disruption of diurnal salivary cortisol rhythm in childhood obesity: relationships with anthropometry, puberty and physical activity

	BMI z-score				WHtR				FM (%)
	β	P	β*	P*	β	P	β*	P*	β	P	β*	P*
Cortisol_08:00	− 0.247	0.036	− 0.247	0.048	− 0.295	0.027	− 0.271	0.030	− 0.238	0.080	− 0.221	0.078
Cortisol_16:00	− 0.066	0.631	− 0 .055	0.692	− 0.077	0.580	− 0.066	0.636	− 0.030	0.831	−0.016	0.907
Cortisol_23:00	0.490	<0.001	0.454	<0.001	0.485	<0.001	0.484	<0.001	0.464	<0.001	0.451	0.001
AUC_{08:00–16:00}	−0.288	0.033	−0.214	0.092	−0.316	0.020	−0.246	0.052	−0.256	0.065	−0.188	0.161
AUC_{16:00–23:00}	0.157	0.265	0.192	0.161	0.188	0.266	0.192	0.162	0.181	0.205	0.229	0.092
AUC_{08:00–23:00}	− 0.197	0.161	−0.123	0.349	− 0.233	0.096	−0.162	0.215	−0.170	0.234	−0.092	0.483
\|DCS\|	−0.350	0.009	−0.327	0.013	−0.384	0.004	−0.366	0.005	−0.322	0.019	−0.313	0.017

* denotes adjusted values for pubertal stage using multiple linear regression. Cortisol variables were logarithmically transformed. BMI z-score body mass index z-score, FM fat mass, WHtR waist-to-height ratio, |DCS| absolute values of diurnal cortisol slope

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