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Table 2 Summary of the 27 studies included in the quantitative analysis

From: Global incidence of Necrotizing Enterocolitis: a systematic review and Meta-analysis

Period

Author/Year

Location

Population at risk

Cases of NEC in population at risk

Population at risk

Incidence

2003–2007

Stoll et al. 2010 [18]

US

VLBW infants

not reporteda

9575

11.0%

1991–1998

Llanos et al. 2002 [3]

US

VLBW infants

47

1425

3.29%

86/87, 92/93, and 98/99

Luig et al. 2005 [4]

Australia

Extremely premature

127

1655

7.67%

2000

Holman et al. 2006 [19]

US- 27 states

VLBW infants

2554

58,810

4.34%

201–2014

Youn 2015 [16]

Korea

VLBW infants

149

2326

6.41%

2011

Qian et al. 2017

China

VLBW infants

221

8727

2.53%

1987–2009

Ahle et al. 2013 [12]

Sweden

VLBW infants

473

17,608

2.68%

2009

Wojkowska-Mach et al. 2014

Poland

VLBW infants

79

910

8.68%

2007

Boo et al. 2012 [14]

Malaysia

VLBW infants

222

3601

6.20%

1998–2004

Wong et al. 2013

Australia

VLBW infants

199

2549

7.81%

87/88, 93/94,99/2000

Fanaroff 2003 [20]

US

VLBW infants

786

12,628

6.23%

2004–2006

Chedid et al. 2008

UAE

VLBW infants

10

173

5.78%

2000–20,209

Agrawel et al. 2015

Singapore

VLBW infants

50

835

6.98%

2008–2010

Patole et al. 2016 [21]

Australia

Extremely premature

16

250

6.40%

2002–2011

Verstreate et al. 2016

Belgium

VLBW infants

158

973

16.23%

2005–2013

Harkin et al. 2017

Finland

Extremely premature

170

1025

6.58%

2007–2012

Andersen et al. 2018

US-California

Extremely premature

1360

14,941

9.10%

2007–2010

Suciu et al. 2017 [22]

Romania

Extremely premature

82

480

17.08%

2010–2014

Patel et al. 2016

US-Atlanta

VLBW infants

44

598

7.34%

2000–2004

Bajwa et al. 2011 [23]

Switzerland

Extremely premature

64

1283

4.95%

1986–1990

Narang et al. 1993 [24]

India

VLBW infants

   

2011–2015

Lodha 2019 [25]

Canada

Extremely premature

412

4680

9%

2006–2016

Boghossian 2018 [26]

United States

VLBW and Extremely premature

18,129

194,736

9%

2007–2015

Persson 2018 [27]

Sweden

Extremely premature

2077

76,360

3%

2008–2012

Suzuki 2018 [28]

Japan

Extremely premature

296

8245

4%

2006–2014

Boghossian 2018 [29]

USA

Extremely premature

10,376

138,869

7%

2010–2015

Beltempo 2018

Canada

Extremely premature

778

9230

8%

  1. a The number of NEC cases was calculated from the incidence and the baseline population for this study